How Many People Survive 5 Years Or More After Being Diagnosed With Female Breast Cancer
Relative survival is an estimate of the percentage of patients who would be expected to survive the effects of their cancer. It excludes the risk of dying from other causes. Because survival statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to treatment can vary greatly.
U.S. 20162020, All Races, Females
What Is Stage 0 Dcis
Stage 0 breast cancer, ductal carcinoma in situ is a non-invasive cancer where abnormal cells have been found in the lining of the breast milk duct. In Stage 0 breast cancer, the atypical cells have not spread outside of the ducts or lobules into the surrounding breast tissue. Ductal Carcinoma In Situ is very early cancer that is highly treatable, but if its left untreated or undetected, it can spread into the surrounding breast tissue.
What Are The Treatment Options For Stage 3 Breast Cancer
Another way a doctor may describe stage 3 breast cancer is if its operable or inoperable. This will determine further treatments.
If a cancer is operable, this means a doctor believes most or all of the cancer can be removed with surgery.
Inoperable cancer is still treatable with systemic therapy, but surgery isnt the right option because doctors feel they cant remove enough cancerous cells.
Treatment options for stage 3 breast cancer may include:
- Surgery: known as a mastectomy, to remove cancerous tissue and also to remove lymph nodes
- Hormone therapy: to slow or stop the growth of cancerous cells, if hormones are driving their growth
- Chemotherapy: involves taking medications to kill fast-growing cancer cells
- Targeted therapy: uses your genes to attack cancer cells without harming healthy cells
Your doctor may also recommend a combination of two or more treatments.
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What Is Stage 4 Breast Cancer
Also known as metastatic breast cancer, the cancer in this stage has spread beyond the breast, underarm and internal mammary lymph nodes to other parts of the body near to or distant from the breast. The cancer has spread elsewhere in the body. The affected areas may include the bones, brain, lungs or liver and more than one part of the body may be involved.
At stage 4, TNM designations help describe the extent of the disease. Higher numbers indicate more extensive disease. Most commonly, stage 4 breast cancer is described as:,
- T: T1, T2, T3 or T4 depends on the size and/or extent of the primary tumor.
- N1: Cancer has spread to the lymph nodes.
- M1: The disease has spread to other sites in the body.
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Triple Negative Breast Cancer
With this type of breast cancer, the breast cancer cells dont have ER+ or PR+ receptors. They dont overproduce the HER2 protein, so hormone therapy isnt very effective.
Instead, triple negative stage 4 breast cancer is usually treated with chemotherapy. Radiation therapy may also be an option, depending on the site of metastasis.
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Survival Statistics For Breast Cancer
Survival statistics for breast cancer are very general estimates and must be interpreted very carefully. Because these statistics are based on the experience of groups of people, they cannot be used to predict a particular persons chances of survival.
There are many different ways to measure and report cancer survival statistics. Your doctor can explain the statistics for breast cancer and what they mean to you.
Dcis Breast Cancer Survival Rate
The DCIS breast cancer treatment prognosis is very good as it is non-invasive. The survival rate usually not depends upon selected treatment option, as treatment is totally depended upon patient condition, means the size of the tumor. The usual finding shows that the general mortality rate from breast cancer after at 20 years of diagnosis is 3.3% 5,6.
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Relative Survival Rate By Stage
The survival rates by stage are based on the stage at the time of diagnosis. Youâve probably been given a number and letter for your cancer stage. Here, the terms localized, regional, and distant are used instead of numbers and letters. Hereâs what they mean and the 5-year relative survival rates for each:
- Localized breast cancer is only in the breast. This includes stage IA , some IIA , and some IIB . The 5-year relative survival rate is 99%.
- Regional breast cancer has spread to nearby tissue or lymph nodes. This includes stage IB , some IIA , some IIB , and all stage III . The 5-year relative survival rate is 86%.
- Distant breast cancer has spread to other parts of the body. This includes stage IV, pronounced âstage 4â). The 5-year relative survival rate is 28%.
Breast Cancer Survival Rates By Stage And Age
The relative 5-year survival rate for breast cancer is 91%. This means that those who have breast cancer are, on average, 91% as likely as those who dont have the disease to live for at least 5 years after their diagnosis. The survival rate is an estimate across the population, and an individuals chance of survival is dependent on their specific characteristics and the nature of the tumour, such as the stage of the breast cancer at diagnosis, the age, gender and the subtype of the breast cancer .
The 5-year survival rate for Stage 1 breast cancer is, on average, 100% and Stage 2 is 95%. For locally advanced cancers the survival rate is 81%, while the 5-year survival rate for Stage 4 is significantly lower at 32%.
The 5-year survival rate also differs depending on the age group. For those aged over 85, the 5-year survival rate is 75%, while for those between 40 and 44 years of age it is 93%.
While the 5-year survival rate post-diagnosis is 91%, the survival rate 10 years after diagnosis of breast cancer is 86%.
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Can You Live 10 Years With Metastatic Breast Cancer
Doctors used to consider metastatic breast cancer , or stage 4, as rapidly progressing in all instances.
Now as many as 10 percent of people with stage 4 breast cancer can achieve long-term and relapse-free survival. This is because of new targeted treatments, like human epidermal growth factor receptor 2 drugs.
Stage 4 is cancer thats spread outside of breast tissue and nearby lymph nodes to other locations in the body.
Understanding more about manageable stage 4 cancer can help doctors know who can benefit from aggressive treatment. There are three categories of information that doctors assess:
- patient characteristics
, the chance of a woman dying from breast cancer is about 2.6 percent.
Breast cancer is common, but in many cases, its curable if its detected early.
Your outlook for breast cancer is better with early detection. Even so, there are people who survive metastatic disease.
According to the ACS , the 10-year relative survival rate for women with breast cancer is 84 percent, and the 15-year survival rate is 80 percent. These statistics include all stages of cancer.
Its important to remember that long-term statistics include people who received their diagnoses many years ago. This means that these statistics dont reflect the more recent improvements in cancer treatment.
A Note About Sex And Gender
Sex and gender exist on spectrums. This article will use the terms, male, female, or both to refer to sex assigned at birth. .
An individuals life expectancy depends on various factors besides the cancer stage.
Some life expectancy measures assess the size of present tumors and how far the cancer cells have spread. However, advancements in tumor biology have changed life expectancy calculations.
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How Quickly Do Breast Cancer Tumors Grow From Stage To Stage
Cancer cells divide and multiply quickly in such a way that as a tumor gets bigger, it divides and grows even faster. The average doubling time for breast cancer tumors is between 50 and 200 days. Breast cancer tumor growth rate is impacted by hormonal factors, such as hormone receptor status and HER2 status.
How Does Staging Relate To Types Of Breast Cancer
In addition to cancer stage, doctors will determine the tumor grade and subtype.
Tumors are graded on a scale of 1 to 3, based on how abnormal the cells appear compared to normal cells. The higher the grade, the more aggressive the cancer, meaning that it tends to be growing quickly.
The subtype is important because treatment and outlook will vary depending on which subtype of breast cancer that you have. Subtypes include:
Survival Rates By Stage
Breast cancer survival rates compare the number of women with breast cancer to the number of women in the overall population to estimate the amount of time women with breast cancer are likely to live after theyre diagnosed.
For example, if the survival rate for a stage of breast cancer during a 5-year period is 90 percent, it means that women diagnosed with that cancer are 90 percent as likely to survive for 5 years following their diagnosis as women who do not have the cancer.
As we mentioned earlier, survival rates are based on information from the SEER database, which the NCI maintains.
SEER does not group breast cancers by stages 0 through 4. Instead, it groups them by the following stages:
- localized: when the cancer has not spread outside of the breast
- regional: when its spread outside the breast to nearby structures or lymph nodes
- distant: when its spread to other parts of the body, such as the liver, lungs, or bones
It should be noted that theres a substantial racial disparity gap in survival rates between white women and Women of Color, especially for late-stage breast cancer diagnoses. The chart below, courtesy of the
What Is The Survival Outlook For Breast Cancer
According to the National Cancer Institute , the percentage of patients surviving five years after diagnosis is:
- 99 percent for breast cancer that is still local to the breast
- 86 percent for breast cancer that has spread just outside the breast
- 29 percent for breast cancer that has spread to more distant parts of the body
The NCI also lists the five-year survival rate for breast cancer overall as 90.6 percent for women and 83 percent for men.
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What Are The Stages Of Breast Cancer
The most widely used system in the U.S. is the American Joint Committee on Cancer TNM system. Medical professionals developed a new eighth edition of this staging system for 2018 that includes results of testing for certain biomarkers, including the HER2 protein, estrogen receptor , and progesterone , and the results of gene expression assays, in addition to the factors described below.
Besides the information gained from the imaging tests, this system also uses the results from surgical procedures. After surgery, a pathologist looks at the cells from the breast cancer as well as from the lymph nodes. They incorporate this information into the staging, as it tends to be more accurate than the physical exam and X-ray findings alone.
The TNM system uses letters and numbers to describe certain tumor characteristics in a uniform manner. This allows healthcare providers to stage cancer and aids communication among healthcare providers. The following is an abbreviated example of the TNM staging system.
T: This describes the size of the tumor. A number from 0 to 4 follows. Higher numbers indicate a larger tumor or greater spread:
- T1: Tumor is 2 cm or less across
- T2: Tumor is 2 cm-5 cm
- T3: Tumor is more than 5 cm
- T4: Tumor of any size growing into the chest wall or skin
N: This describes the spread to lymph nodes near the breast. A number from 0 to 3 follows.
M: This letter is followed by a 0 or 1, indicating whether cancer has spread to other organs.
The Tnm System For Staging Breast Cancer
The AJCCs addition of the letters T, N, and M for anatomic breast cancer staging adds more information to a breast cancer diagnosis. Heres what they mean:
- T : The tumor grade shows a higher number for a larger size or density.
- N : Nodes refers to lymph nodes and uses the numerals 0 to 3 to give information about how many lymph nodes are involved in the cancer.
- M : This refers to how the cancer has spread beyond the breast and lymph nodes.
The AJCC also added clarifications in staging for ER, PR, and HER2 expression and also genetic information.
Ultimately, this means someone diagnosed with stage 3 breast cancer can receive more information from their breast cancer staging than ever before.
No matter the stage, the best source of information about your individual outlook is your own oncology team.
Getting the right treatment and the support you need can help you navigate the challenges of being diagnosed with stage 3 breast cancer.
What Is The Future Of Treating Breast Cancer
In clinical trials, immunotherapy has yielded positive results and demonstrated increased response rates in patients with both early and late stages of breast cancer. Immunotherapy is approved for patients with advanced triple-negative cancer, which often grows and spreads faster than other types of breast cancer.
Stage 3 Breast Cancer
Stage 3 breast cancer has spread outside the breast but not to distant sites. The cancer is typically in nearby lymph nodes or skin.
Stage 3 breast cancer is typically harder to treat than earlier stages. This, however, ultimately depends on several factors, including:
- hormone receptivity
A doctor can help a person better understand the stage of cancer and how that will affect treatment options and their outlook.
Healthcare professionals distinguish between the following stages of stage 3 breast cancer:
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Will I Die Of Breast Cancer
This is a difficult question to answer early in your cancer care but it is still worth asking. Many people just diagnosed with cancer have no idea how much of a risk to their life their unique situation poses. Most breast cancers carry a low risk of recurrence, especially early-stage cancers. The answer is usually reassuring.
What Does It Mean To Have Stage 1 Breast Cancer
In Stage 1 breast cancer, cancer is evident, but it is contained to only the area where the first abnormal cells began to develop. The breast cancer has been detected in the early stages and can be very effectively treated.
Stage 1 can be divided into Stage 1A and Stage 1B. The difference is determined by the size of the tumor and the lymph nodes with evidence of cancer.
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Factors That Influence Breast Cancer Prognosis
The stage of a persons breast cancer is an important predictor of their prognosis. The stages of the disease range from 0 to 4 . Stages can also have substages, denoted by a letter . These are based on factors such as tumor size and types of cancer cells. A doctor will determine a persons stage at diagnosis, based on how far the cancer has spread throughout the body.
For early-stage and locally advanced breast cancer , a doctor will consider the following variables when estimating a persons prognosis:
- Tumor grade, which pertains to how abnormal the cancer cells look under a microscope compared to normal cells
- How many lymph nodes contain cancer cells
Additionally, there are important genetic features present in some breast cancers that also factor into treatment options and prognosis:
- HER2 status Whether or not the cancer cells contain high levels of a protein called human epidermal growth factor receptor 2
- Hormone receptor status Whether the cancer cells contain the estrogen receptor or progesterone receptor
- The genetic profile of the tumor, as determined by a diagnostic test such as Oncotype Dx
Early detection of breast cancer leads to a better prognosis. If the breast cancer has spread to other parts of the body, then it is known as metastatic breast cancer or stage 4 breast cancer. The presence of metastases has a negative impact on breast cancer survival.
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When Should I Go To The Emergency Room
You might also have unusually strong side effects from your cancer treatment. While your healthcare provider likely gave you medication to help control your side effects, you should go to the emergency room if your side effects continue despite medication.
Many cancer treatments affect your immune system, increasing the chance you will develop infections. Symptoms that might require an emergency room visit during treatment are:
- Fever of 100.5 and above.
- Persistent nausea and vomiting.
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Interactive Statistics With Seer*explorer
With SEER*Explorer, you can…
- Create custom graphs and tables
SEER*Explorer is an interactive website that provides easy access to a wide range of SEER cancer statistics. It provides detailed statistics for a cancer site by gender, race, calendar year, age, and for a selected number of cancer sites, by stage and histology.
Stage 1b Breast Cancer Means One Of The Following Descriptions Applies:
Lymph nodes have cancer evidence with small clusters of cells between the approximate size of a pinprick to the approximate width of a grain of rice .
AND EITHER No actual tumor is found in the breast.
OR The tumor is smaller than the approximate size of a peanut .
Similar to stage 0, breast cancer at this stage is very treatable and survivable. When breast cancer is detected early, and is in the localized stage , the 5-year relative survival rate is 100%.
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