Survival Of Breast Cancer Based On Stage
Statistics are given below for the overall survival rates for breast cancer based on certain stages of disease development.
I made this page many years ago, when there was nothing like this data available on the internet. Recently this page has been up-dated with the most recent statistics that we can find. Prognosis will be even better than the numbers here suggest because modern targeted treatments have improved a lot.
Breast cancer staging is determined by many factors and these include:-
- The presence and size of a tumor
- Whether the tumor is node negative or positive, this means whether lymph nodes are involved or not
- If the cancer has metastasized beyond the breast
If breast cancer is diagnosed and it is determined that there is no metastasis to the lymph nodes then the chances of survival are extremely good.
Once breast cancer has spread to the lymph nodes the mode of treatment tends to shift to the chemotherapy medicines, and the odds of survival are somewhat lower.
What Do Cancer Stages And Grades Mean
The stage of a cancer describes the size of a tumour and how far it has spread from where it originated. The grade describes the appearance of the cancerous cells.
If you’re diagnosed with cancer, you may have more tests to help determine how far it has progressed. Staging and grading the cancer will allow the doctors to determine its size, whether it has spread and the best treatment options.
A Note About Statistics
Survival rates are statistics. As such, they tend to tell us how the average person will do with an average triple-negative breast cancer. But people and tumors arent statistics. Some people will do better, and some people will do worse.
Very importantly, statistics are usually several years old. In order to calculate five-year survival rates, a person would have to have been diagnosed at least five years prior, and there is lag time. The treatment of triple-negative breast cancer is changing, and new drugs have been approved.
According to research from the National Cancer Institute , the number of women living with metastatic breast cancer in the United States is increasing at the same time, women with metastatic disease are living longer, especially younger women.
The research was published online on May 18, 2017 by the journal Cancer Epidemiology, Biomarkers & Prevention. Read the abstract of Estimation of the Number of Women Living with Metastatic Breast Cancer in the United States.
Metastatic breast cancer is breast cancer that has spread to parts of the body away from the breast, such as the bones or liver. Metastatic breast cancer is stage IV cancer. A woman can be diagnosed with metastatic disease when first diagnosed. Breast cancer also can come back in a part of the body away from the breast. This is called metastatic recurrence.
The study compared 5-year survival rates from 1992 to 1994 and from 2005 to 2012:
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Survival Statistics For Breast Cancer
Survival statistics for breast cancer are very general estimates and must be interpreted very carefully. Because these statistics are based on the experience of groups of people, they cannot be used to predict a particular persons chances of survival.
There are many different ways to measure and report cancer survival statistics. Your doctor can explain the statistics for breast cancer and what they mean to you.
Clinicopathological Characteristics Of Patients
Among 491,913 patients originally identified from SEER database, cases of 33,339 TP-FBCs and 336 TP-MBCs from 2010 to 2017 were included in our study. According to the percentage of TP-FBC/TP-MBC to total FBC/MBC at each year , we firstly showed the trends of the subsets in 8 years . Generally, the subtype of TPBC was more prevalent in males than that in females with the exception of 2012.
Clinical pathological characteristics of TP-MBC compared with TP-FBC were summarized in Table . TP-MBC patients are significantly older than TP-FBC , patients older than 65years account for almost half in TP-MBC. TP-MBC had less Asian/pacific islanders , more ductal carcinoma , higher clinical stage as well as T stage , N stage , M stage . However, there was no significant difference in tumor grade and surgery status between TP-MBC and TP-FBC.
Table 1 Clinical pathological characteristics of TP-MBC compared with TP-FBC
In Table , data of distant organ metastasis in TP-MBC and TP-FBC was shown. Compared with TP-FBC, TP-MBC patients had higher proportions of bone metastasis and lung metastasis . Significant difference was not found in the brain metastasis or liver metastasis between TP-MBC and TP-FBC.
Table 2 Comparison of distant organ metastasis patterns in TP-MBC and TP-FBC
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What Are The Types Of Breast Cancer Recurrence
If you develop cancer in the opposite, untreated breast , you receive a new breast cancer diagnosis. This isnt the same as breast cancer recurrence.
When breast cancer returns, it may be:
- Local: Cancer returns in the same breast or chest area as the original tumor.
- Regional: Cancer comes back near the original tumor, in lymph nodes in the armpit or collarbone area.
- Distant: Breast cancer spreads away from the original tumor to the lungs, bones, brain or other parts of the body. This is metastatic cancer, often referred to as stage 4 breast cancer.
Facts About Metastatic Cancer Survival Rate
Metastatic cancer survival rate is very important to patients. This refers to how they can deal with the cancer in order to survive. Prognosis of any cancers especially at this point is extremely relevant.
Metastatic Cancer Survival Rate
The hope to survive is what patients are concerned about. Surviving from metastatic cancer is the goal of every patient.
Metastatic cancer, which is also known as metastasis, is the spreading of cancerous cells to various organs and other tissues. These cells extend through the blood stream. If cancer cells begin to spread, other organs become affected which may result to damage. Generally, this condition exists during later stages. The essential thing that you must consider is the malignant cells. These cells should be well controlled so the disease will not worsen. Treating this disease right way is vital so metastatic cancer survival rate lung cancer, brain cancer or no matter what type would increase.
Improving metastatic cancer survival rate uterine is not difficult at all. With complete and proper treatments, any patient of uterine cancer at this late stage can still have a huge chance of surviving. The survival rate of this type of cancer is not that low at all compared to others such as brain and liver cancer. Metastatic cancer survival rate brain and metastatic cancer survival rate liver are somewhat lower than metastatic uterine cancer.
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Survival Rates And Mortality Rates
Survival depends on mortality. You start with 100 percent of the people in the group.
100 percent mortality rate = survival rate
Say, the mortality rate in the group of people is 5 percent. Survival would be 95 percent .
Similarly, the number of people in a group who survive depends on the number of people who die. Say, 500 people are in the group and 1 person dies. This means 499 people survived .
What Is Stage Iv Breast Cancer
Stage IV is the most advanced stage of breast cancer. It has spread to nearby lymph nodes and to distant parts of the body beyond the breast. This means it possibly involves your organs such as the lungs, liver, or brain or your bones.
Breast cancer may be stage IV when it is first diagnosed, or it can be a recurrence of a previous breast cancer that has spread.
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Are There Any Statistics On Recurrence Rates Or Incidence Of Metastasis
As mentioned, it is very difficult to find statistics on metastatic breast cancer that has recurred after initial diagnosis. However, these cases represent a large proportion of Stage IV breast cancer cases and overall deaths.
Most of the statistical data on Stage IV or metastatic breast cancer is from those women presenting at diagnosis. According to the Metastatic Breast Cancer Network in 2012 new cases of Stage IV breast cancer were between 13,776 to 22,096.
The number of breast cancer recurrences at Stage IV is estimated to be between 20% and 30% of all breast cancer diagnoses.
Stage 1b Cervical Cancer
Cervical cancer in the 1B stage consists of larger cancer cells than the previous stage. It can often be seen without a microscope. It has two phases, 1B1 and 1B2. In the 1B1 stage, cancer cells have not reached 4cm yet. In 1B2 phase, cancer cells have reached 4cm. At this stage, cancer cells have not yet metastasized and spread.
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What Is The Survival Rate For Invasive Ductal Carcinoma
The survival rate for this malignancy varies depending on the stage the patient is at. For example:
- If invasive ductal carcinoma has not spread beyond the breast, the five-year survival rate is approximately 99%.
- If the cancer has spread to nearby structures or lymph nodes, the five-year survival rate is approximately 86%.
- If the malignancy has spread to a distant area of the body, the five-year survival rate is approximately 27%.
When considering these numbers, its important to remember that they are just general benchmarks and should not be used to predict a specific persons chances of survival. There are a number of factors that can influence a patients prognosis, such as:
- Whether the cancer is new or recurring
- How far the cancer had progressed by the time it was diagnosed
- The cancers hormone-receptor status and HER2 status
- How quickly the cancer cells are growing
- How the cancer is responding to treatment
- The patients age, menopausal status and overall health
Plus, reported survival rates will of course be dated, and as newer treatment methods are developed, these rates will likely improve.
Stage 0 Breast Cancer
What is Stage 0 breast cancer?
Stage 0 breast cancer is when the cells that line the milk ducts have become cancerous. This type of cancer is called ductal carcinoma in situ , or non-invasive or pre-invasive breast cancer.
At this stage, the cancer has not spread to surrounding tissues. And while its considered non-invasive, its important to remember that it can still become invasive and spread beyond the milk ducts if it isnt treated.
What are the options for Stage 0 breast cancer treatment?
- Surgery Breast surgery is often the first step at Stage 0. Depending on the size of the tumor, how fast the cancer appears to be growing and your personal preferences, there are two types of surgical options:
- Lumpectomy A lumpectomy is a targeted surgery that removes the lump or tumor in question, and a small amount of normal tissue around it. This is commonly referred to as breast conservation surgery . In the United States, most women with Stage 0 breast cancer undergo a lumpectomy followed by radiation therapy.
- Mastectomy If the cancer has spread throughout the ducts and affects a large part of the breast, doctors may recommend a mastectomy. With this surgery, the entire breast is removed and possibly some lymph nodes as well.
What is the Stage 0 breast cancer treatment timeline?
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Expert Review And References
- American Cancer Society. Breast Cancer. 2015: .
- de Boer M, van Dijck JA, Bult P, Borm GF, Tjan-Heijnen VC. Breast cancer prognosis and occult lymph node metastases, isolated tumor cells, and micrometastases. Journal of the National Cancer Institute. Oxford University Press 2010.
- Lonning PE. Breast cancer prognostication and prediction: are we making progress?. Annals of Oncology. Oxford: Oxford University Press 2007.
- Morrow M, Burstein HJ, and Harris JR. Malignant tumors of the breast. DeVita VT Jr, Lawrence TS, & Rosenberg SA. Cancer: Principles and Practice of Oncology. 10th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins 2015: 79: 1117-1156.
- Tripathy D, Eskenazi LB, Goodson, WH, et al. Breast. Ko, A. H., Dollinger, M., & Rosenbaum, E. Everyones Guide to Cancer Therapy: How Cancer is Diagnosed, Treated and Managed Day to Day. 5th ed. Kansas City: Andrews McMeel Publishing 2008: pp. 473-514.
The Stages Of Breast Cancer And Your Treatment Options
Compared to most other cancers, staging breast cancer is more complex. And when it comes to treating breast cancer, there isnt a one-size-fits-all approach. Your treatment plan should be created especially for you and be coordinated across specialists and thats where your cancer care team comes in.
At HealthPartners, we believe cancer treatment and care is best managed by a group of doctors and specialists in whats known as multidisciplinary conferences. This is where breast surgeons, oncologists, radiologists, pathologists and other members of your care team gather to discuss the best treatment sequence for you.
Below we dive into the treatment options your care team might recommend at various breast cancer stages.
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Where Do These Numbers Come From
The American Cancer Society relies on information from the Surveillance, Epidemiology, and End Results database, maintained by the National Cancer Institute , to provide survival statistics for different types of cancer.
The SEER database tracks 5-year relative survival rates for breast cancer in the United States, based on how far the cancer has spread. The SEER database, however, does not group cancers by AJCC TNM stages . Instead, it groups cancers into localized, regional, and distant stages:
- Localized: There is no sign that the cancer has spread outside of the breast.
- Regional: The cancer has spread outside the breast to nearby structures or lymph nodes.
- Distant: The cancer has spread to distant parts of the body such as the lungs, liver or bones.
How Breast Cancer Is Staged
Breast cancer staging ranges from 0 to 4, making a total of 5 possible stages. As of 2018, the standard for staging breast cancer now takes into consideration 7 factors to reach a more exact diagnosis with varying degrees of treatment options. According to Breastcancer.org, the following parameters help your physician to reach a decision on the degree of the cancer, treatment and prognosis.
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Stage 1 Breast Cancer: Treatment And Prognosis
Breast cancer is classified into different stages ranging from 0 to 4. Staging is based on the tumors size and whether tumor cells have spread to other parts of the body. Determining your cancers stage can help your doctor determine your prognosis and the best treatment options.
The TNM staging system which stands for tumor, node, and metastasis is generally used for breast cancer staging. The system stages tumors based on:
- Tumor How large is the primary tumor?
- Node Are there cancer cells in lymph nodes?
- Metastasis Has the cancer metastasized, or spread, to other parts of the body?
Each letter is assigned a number, often with a letter following it. A lower number corresponds to early stage breast cancer, and a higher number indicates more advanced breast cancer.
Other information is also used to better understand the stage of the cancer. This can include:
- Hormone receptor status Whether the cancer contains estrogen receptors or progesterone receptors, proteins that respond to hormones in the body
- Tumor grade A measure of how abnormal the cancer cells look compared to normal cells
- HER2 status Whether the cancer has high levels of a protein called HER2
- Oncotype DX score Results of a genetic test used to predict if a cancer might progress to a more serious form of cancer
Following breast cancer diagnosis, a doctor will determine the most effective treatment based on the cancers stage.
How Do Breast Cancer Cells Spread Around The Body
Breast cancer cells travel through the body like any other cancer cells. Firstly, cancer cells can invade neighbouring healthy tissue. Following this, the cancer cells then invade local lymph nodes or blood vessels.
When breast cancer spreads to the axillary lymph nodes this is still a relatively early stage of metastasis, and potentially curable.
The cancer cells will typically travel through the lymphatic system or blood vessels to other distant parts of the body.
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How Grade Affects Treatment Options
Your treatment team will consider the grade of your cancer when deciding which treatment to offer you.
If you have grade 3 breast cancer, youre more likely to be offered chemotherapy. This is to help destroy any cancer cells that may have spread as a result of the cancer being faster growing.
Chemotherapy is less likely for grade 1 and grade 2 cancers.
The grade of your cancer alone will not determine what treatment youre offered. Your treatment team will consider the grade alongside all other information about your cancer when deciding on the best treatment options for you.
Find out more about breast cancer and prognosis.
What Is Stage 1 Breast Cancer
Invasive breast cancer occurs when cancer cells have started to move from their original location usually in the milk ducts into the surrounding breast tissue. Stage 1 breast cancer is the earliest form of invasive breast cancer. It may further be classified into substages: stage 1a and stage 1b.
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