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Stage 4 Breast Cancer Survival Rate With Treatment

What Are The Treatments For Cancer

Clinical Trial Helps Breast Cancer Patient

Others aim to stop cancer growth. Treatments at this stage might include: chemotherapy, although it can become too risky when cancer spreads far. radiation therapy, which can shrink tumors and help with symptoms. immunotherapy, which helps the bodys immune system fight the cancer. surgery to remove the cancer.

From Cured To Stage 4

Others, like Teri Pollastro, a 54-year-old stage 4 patient from Seattle, respond surprisingly well.

Diagnosed with early stage ductal carcinoma in situ in 1999, Pollastro underwent a mastectomy but did not receive chemotherapy, radiation or tamoxifen, since her cancer was ER negative.

âThey used the C-word with me, they told me I was cured,â she said. âEvery time I went back to my oncologist, he would roll his eyes at me when I had questions.â

In 2003, Pollastro switched to Seattle Cancer Care Alliance where she saw Dr. Julie Gralow, a breast cancer oncologist and clinical researcher at Fred Hutchinson Cancer Research Center. Gralow discovered Pollastroâs cancer had metastasized to her liver.

âMy husband and I were in shock,â said Pollastro of her mets diagnosis. âYou donât go from being cured to stage 4.â

Pollastro went on Herceptin, a type of immunotherapy for women with HER2-positive metastatic breast cancer, and did six months of chemotherapy.

âI felt better right away with the treatment,â she said. âBut the problem is, it stopped . Thatâs what you can expect with mets. And thereâs always some residual cancer. And that starts percolating.â

And along with mets, she also had to deal with many misconceptions regarding her disease.

The Mercer Island, Washington, mother of two, who often counsels newly diagnosed patients, sometimes even found it difficult to relate to early stage breast cancer survivors.

Survival Rates For Breast Cancer

Survival rates can give you an idea of what percentage of people with the same type and stage of cancer are still alive a certain amount of time after they were diagnosed. They cant tell you how long you will live, but they may help give you a better understanding of how likely it is that your treatment will be successful.

Keep in mind that survival rates are estimates and are often based on previous outcomes of large numbers of people who had a specific cancer, but they cant predict what will happen in any particular persons case. These statistics can be confusing and may lead you to have more questions. Talk with your doctor, who is familiar with your situation, about how these numbers may apply to you.

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What Is Breast Cancer Staging

Breast cancer staging is the determination of the extent and spread of the cancer. An individual’s health care team uses stages to summarize the extent of the cancer in a standardized way that is recognized by all health care providers. They use this staging to determine the treatment most appropriate for the type of cancer. Cancer staging helps to determine the prognosis, or outlook, of a cancer, including rates of recurrence and survival rates.

Progression During Hormone Therapy


For hormone receptor-positive cancers that were being treated with hormone therapy, switching to another type of hormone therapy sometimes helps. For example, if either letrozole or anastrozole were given, using exemestane, possibly with everolimus , may be an option. Another option might be using fulvestrant or a different aromatase inhibitor, along with a CDK inhibitor. If the cancer has a PIK3CA mutation and has grown while being treated with an aromatase inhibitor, fulvestrant with alpelisib might be considered. If the cancer is no longer responding to any hormone drugs, chemotherapy immunotherapy, or PARP inhibitors might be options depending on specific features of the cancer or any gene changes that might be present.

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What Is The Chance I Could Die In The Next 5 Years

The average 5-year survival rate for all people with breast cancer is 89%. The 10-year rate is 83%, and the 15-year rate is 78%. If the cancer is located only in the breast , the 5-year survival rate is 99%. More than 70% of breast cancers are diagnosed at an Early Stage.

All survival statistics are primarily based on the stage of breast cancer when diagnosed. Some of the other important factors are also listed below that affect survival.

Stage 0 breast cancer can be also described as a pre-cancer. If you have DCIS you can be quite confident you will do well. DCIS does not spread to other organs. What can be concerning is when an invasive cancer grows back in the area of a prior lumpectomy for DCIS. This type of local recurrence does carry a risk to your life. Luckily, this does not happen frequently. Also, be aware that those who have had DCIS in the past are at a higher risk for developing an entirely new, invasive breast cancer. Take our video lesson on Non-Invasive DCIS to learn more.

Stage I invasive breast cancer has an excellent survival rate. The chance of dying of Stage I breast cancer within five years of diagnosis is 1 to 5% if you pursue recommended treatments.

Stage II breast cancer is also considered an early stage of breast cancer. There is a slightly increased risk to your life versus a Stage I breast cancer. Altogether, the risk of Stage II breast cancer threatening your life in the next 5 years is about 15%.

Prognosis For Metastatic Breast Cancer

Metastatic breast cancer isnt the same for everyone who has it. According to the National Breast Cancer Foundation, your symptoms at stage 4 will depend on the degree to which the cancer has spread in your body.

Although metastatic breast cancer has no current cure, it can be treated. Getting the right treatment can increase both your quality of life and longevity.

Life expectancy for breast cancer is based on studies of many people with the condition. These statistics cant predict your personal outcome each persons outlook is different.

The following factors can affect your life expectancy with metastatic breast cancer:

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Some Cancers Are Rising

Although the death rate for cancer has been on a steady decline, the new report also highlights that new cases of breast, uterine and prostate cancer have been of concern and rising in the United States.

Incidence rates of breast cancer in women have been increasing by about 0.5% per year since the mid-2000s, according to the report.

Uterine corpus cancer incidence has gone up about 1% per year since the mid-2000s among women 50 and older and nearly 2% per year since at least the mid-1990s in younger women.

The prostate cancer incidence rate rose 3% per year from 2014 through 2019, after two decades of decline.

Knudsen called prostate cancer an outlier since its previous decline in incidence has reversed, appearing to be driven by diagnoses of advanced disease.

On Thursday, the American Cancer Society announced the launch of the Impact initiative, geared toward improving prostate cancer incidence and death rates by funding new research programs and expanding support for patients, among other efforts.

Will I Die Of Breast Cancer

Breast Cancer Survival Rate

This is a difficult question to answer early in your cancer care but it is still worth asking. Many people just diagnosed with cancer have no idea how much of a risk to their life their unique situation poses. Most breast cancers carry a low risk of recurrence, especially early-stage cancers. The answer is usually reassuring.

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Living With Stage : The Breast Cancer No One Understands

Leer en español.

Editor’s note: We’re bringing back this piece from October 2014 for Metastatic Breast Cancer Awareness Day and to honor Jody Schoger, featured in the story. Schoger died of metastatic breast cancer in May. Want to learn more about MBC? Look for our tweets at the Northwest Metastatic Breast Cancer Conference this Saturday at Fred Hutch.

A no-nonsense Texan of 60 years, Jody Schoger* has a very no-nonsense way of educating people about her metastatic breast cancer.

âSomeone will say, âWhen are you done with treatment?â and Iâll tell them, âWhen Iâm dead,ââ said Schoger, a writer and cancer advocate who lives near Houston. âSo many people interpret survivorship as going across the board. That everybody survives cancer now. But everybody does not survive cancer.â

An estimated 155,000-plus women in the U.S. currently live with âmets,â or metastatic breast cancer. This type of cancer, also called stage 4 breast cancer, means the cancer has metastasized, or traveled, through the bloodstream to create tumors in the liver, lungs, brain, bones and/or other parts of the body. Between 20 and 30 percent of women with early stage breast cancer go on to develop metastatic disease. While treatable, metastatic breast cancer cannot be cured. The five-year survival rate for stage 4 breast cancer is 22 percent median survival is three years. Annually, the disease takes 40,000 lives.

Where Do These Numbers Come From

The American Cancer Society relies on information from the Surveillance, Epidemiology, and End Results database, maintained by the National Cancer Institute , to provide survival statistics for different types of cancer.

The SEER database tracks 5-year relative survival rates for breast cancer in the United States, based on how far the cancer has spread. The SEER database, however, does not group cancers by AJCC TNM stages . Instead, it groups cancers into localized, regional, and distant stages:

  • Localized: There is no sign that the cancer has spread outside of the breast.
  • Regional: The cancer has spread outside the breast to nearby structures or lymph nodes.
  • Distant: The cancer has spread to distant parts of the body such as the lungs, liver or bones.

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If Im 70 Or Older Will Invasive Breast Cancer Be Fatal

Though a cancer diagnosis is scary at any age, older adults may feel more vulnerable. But Tran says there are reasons not to panic.

In patients 70 years old or older, most of the time, the invasive cancer is hormone receptor positive, which means it is a slower-growing cancer.

Most patients treated for invasive breast cancer survive, she says. Even when you are diagnosed at an older age, you can successfully complete your therapy, go on living and eventually die from causes other than breast cancer.

This is especially true for those who are in good general health at the time of their diagnosis and who are able to care for themselves.

Stage 4 Prostate Cancer And Treatments

Breast Cancer Stage 4

A stage 4 prostate cancer diagnosis means that the cancer has spread beyond the prostate, usually to either the adrenal glands, bones, lungs, or liver.

Treatment for stage 4 prostate cancer can involve removing the prostate and providing hormone therapy. Hormone blocking therapy reduces the amount of testosterone in the body, in order to help slow the growth of the cancer or shrink it. This type of hormone therapy is sometimes used alongside testicle removal, on a case by case basis. Radiation therapy and chemotherapy are also occasionally used.

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Demographic And Clinical Variables

The relationship between metastatic sites and clinical characteristics, including age at diagnosis, year of diagnosis, race, marital status, tumor grade, tumor size, nodal status, subtype, and treatment was analyzed. Initial metastatic sites were registered as single or multiple and were categorized as bone-only, lung-only, liver-only, brain-only, other-only and multiple metastasis . Overall survival was calculated from the date of diagnosis to the date of death due to any cause, the date of last follow-up, or December 31, 2015. Breast cancer specific survival was measured as the time from the date of diagnosis to the date of death attributed to breast cancer. Both overall survival and breast cancer specific survival were used as endpoints.

Stage 4 Cancer Treatment Options

When it comes to treating Stage 4 cancer, there are a few different commonly used methods, which we will examine below.

Please keep in mind that whether or not an individual is a candidate for the following treatment options depends upon certain variables so it is always best to consult your doctor directly to find out which treatment option is most appropriate for you.

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Survival For All Stages Of Breast Cancer

Generally for women with breast cancer in England:

  • Around 95 out of every 100 women survive their cancer for 1 year or more after diagnosis
  • Around 85 out of every 100 women will survive their cancer for 5 years or more after diagnosis
  • Around 75 out of every 100 women will survive their cancer for 10 years or more after diagnosis

Cancer survival by stage at diagnosis for England, 2019Office for National Statistics

These statistics are for net survival. Net survival estimates the number of people who survive their cancer rather than calculating the number of people diagnosed with cancer who are still alive. In other words, it is the survival of cancer patients after taking into account that some people would have died from other causes if they had not had cancer.

Metastatic Breast Cancer Treatment

Understanding Breast Cancer Survival Rates

Treatment for metastatic breast cancer often is based on systemic therapies, which use drugs rather than surgery or radiation. Metastases treatments are designed to shrink tumors and slow their growth, help ease symptoms and improve quality of life. Treatment may change, such as when one therapy stops working, or the side effects become too uncomfortable. Rather than having only one treatment, most patients undergo several treatments combined to help fight the cancer.

The four broad categories of drug-based treatments are:

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What Do You Mean By Survival Rate

A number of factors influence the survival rate. Survival rates are estimates based on the outcomes of vast numbers of people who have previously had certain malignancies, but they cannot foretell what will happen in any given person’s case.

If you have any concerns, you should always visit your doctor.

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Solid Tumors Vs Liquid

Cancer can occur in one of two different forms: solid tumors or liquid cancers.

When a cancer forms a solid mass, or tumorit is referred to as a solid tumor cancer. In this type of cancer, tumorous masses form in a specific bodily organ, such as the breasts, lungs, or ovariesfor example. Solid tumors can occur anywhere in the body.

On the other hand, liquid cancers, or liquid tumors, refer to those that specifically affect the blood, bone marrow, or lymph nodes of the body only. Leukemia, Lymphoma, and Myeloma are examples of liquid cancers.

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Diagnosis Of Stage 4 Breast Cancer

If you are diagnosed with breast cancer, you may have further tests to determine the extent that the cancer has spread throughout the body. This is called staging. It helps you and your doctors decide on the best treatment options for you.

In addition the numbered staging system, the TNM staging system is also commonly used for breast cancer staging.

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A Second Cancer Diagnosis

Breast Cancer Survival: Statistics and Facts

As a survivor, Chelle knew there is always a risk of breast cancer coming back. In 2017, she received the bad news. Despite years of remission and the removal of so many lymph nodes, there was a mass in the remaining axillary lymph nodes under her arm.

I said, Ive had enough chemo and enough radiation, Chelle said. I just didnt want anymore.

Instead, her oncologist prescribed a targeted therapy combined with a hormone therapy for treatment. One of the medications was delivered to Chelles home and one time it got lost.

RMCC told me to just come to the office and get it there until FedEx was able to sort out the issue, Chelle said. RMCC was and is ready and willing to help in any way that they can.

Chelle remained stable until 2021, when another scan showed she had lymphoma, and it was affecting her thyroid.

Chelle was taken off the targeted therapy and did two cycles of R-CHOP chemotherapy. Then in December she ended up in the hospital with a fractured sternum.

Her doctors said she was cancer free and discontinued the R-CHOP. But thats what they said in 2006, so when they say, you know, no more cancer, in the back of my mind, I say, yeah, okay, Chelle said.

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In Remission And Staying Positive

Now 65 and retired, Chelle returns to RMCC to have her port flushed every six weeks. A port is a small device left under a patients skin to help with blood draws, injections, and infusions. Chelle also undergoes regular imaging to make sure her cancer has not returned. Every three months, she checks in with Dr. Sujatha Nallapareddy and her physician associate John Novak.

Still, Chelles health is fragile. She remains on oxygen at night and is also on dialysis three times a week.

I will be on it for the rest of my life, Chelle said. But at least my cancer treatments are done, and my visits are now just to keep on top of the cancer, should anything show up again which is good.

Chelle has also dealt with basal squamous skin cancers on her legs and other parts of her body, which have had to be removed.

Though the journey has been challenging, Chelle is thankful for her team at RMCC.

I just cant say enough good things about all my RMCC providers, Chelle said, praising PET scan staff who always makes sure she has blankets so she can stay warm.

Despite everything shes faced, Chelle remains upbeat. Shes repeatedly survived cancer. She was able to see her three grandchildren grow up and RMCC has been by her side for it all.

My journey has been awesome, Chelle says. Yes, its been filled with cancer, but Rocky Mountain is there, should I need anything.

Make an appointment to talk to a provider about breast cancer treatment.


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