What Is The Prognosis For Stage 2 Breast Cancer
The 5-year breast cancer survival rate for stage 2 Breast cancer diagnosed in the U.S. varies according to size of the tumor and whether or not cancer has spread to the lymph nodes.
If the breast cancer is under 2 centimeters in diameter and has spread to the lymph nodes under the arm , it is stage IIA breast cancer and the survival rate is 88%-92% .
If the breast cancer is between 2-5 centimeters but has not spread, it is also called stage IIA.
If the breast cancer is between 2-5 centimeters in diameter and has spread to the lymph nodes, it is called stage IIB breast cancer and the 5-year breast cancer survival rate is 76%-81%.
If the breast cancer is larger than 5 centimeters but has not spread beyond the breast, it is also called stage IIB
Up to 29% of diagnosed breast cancer is Stage 2 breast cancer for white women and 36% for black women. An average of 62% of all breast cancer is diagnosed when it is still localized to the breast area or Stage 1 breast cancer. If the cancer is detected early enough, such as Stage 1 breast cancer, then the 5-year breast cancer survival rate is as high as 98%-100%. Early detection is the most important way to save the lives of cancer patients.
What Is A 5
A relative survival rate compares women with the same type and stage of breast cancer to women in the overall population.For example, if the 5-year relative survival rate for a specific stage of breast cancer is 90%, it means that women who have that cancer are, on average, about 90% as likely as women who dont have that cancer to live for at least 5 years after being diagnosed.
What Are The Chances Of Breast Cancer Recurring
Despite huge advancements in breast cancer screening, early detection and treatment, a percentage of breast cancers will recur and spread to distant sites.
Although at the moment, it is almost impossible to say which cancers will recur and at what time period from diagnosis, there are a few factors that are known to increase the risk for recurrence.
These risk factors include:-
- Lymph node involvement and number of lymph nodes affected at the time of diagnosis
- Tumor Size at the time of diagnosis
- A subtype of Breast Cancer and hormonal receptor Status
- The time span from the initial diagnosis to recurrence of breast cancer
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How Treatment Can Impact Survival Of Early Stage Breast Cancer
In most cases, the earlier breast cancer is first diagnosed and treated, the better the chance of survival. Cancer cells often become more difficult to treat and may develop drug resistance once they spread. The aim of treatment for Stage 1 and 2 breast cancer is to remove the breast cancer, and any other cancer cells that remain in the breast, armpit or other parts of the body but cannot be detected. Having treatment at this stage can also reduce the risk of the cancer coming back.
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A Little Bit More About Staging And Survival Rates
In general, the lower the grade of the breast cancer on diagnosis the better the prognosis rate.
Obviously if the tumor can be detected and treated before the size of 2cm and before it has affected nearby lymph nodes, then the overall survival rate is very good, as we have seen.
A recent 2012 medical study found tumor size to be a strong predictor for 15 year survival rates in both node-negative and positive groups.
Furthermore, this study shows that tumor size had a greater impact on 15 year survival in the node positive group. The research concluded that screening for more advanced stages of breast cancer could well be more beneficial than for those at an earlier stage.
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How Can I Prevent Breast Cancer Recurrence
Healthcare providers dont know why some people experience breast cancer recurrence. A recurrence isnt your fault. You didnt do anything wrong to cause it or fail to do something more to prevent it.
Certain medications may reduce the risk of breast cancer recurrence in people who have early stage breast cancer. For estrogen-receptive breast cancer, hormonal therapies including tamoxifen or aromatase inhibitors block either the activity of estrogen or the bodys production of estrogen. Chemotherapy may also be recommended to reduce risk of breast cancer recurrence.
Early diagnosis may make it easier to treat a recurrence. Follow your healthcare providers recommendations for mammograms and other screenings. You should also perform regular breast self-exams. Get familiar with how your breasts look and feel so you can see your provider quickly if you notice changes. And remember that most breast changes occur for reasons other than cancer.
What Does It Mean To Have Stage 3 Breast Cancer
Stage 3 cancer means the breast cancer has extended to beyond the immediate region of the tumor and may have invaded nearby lymph nodes and muscles, but has not spread to distant organs. Although this stage is considered to be advanced, there are a growing number of effective treatment options.
This stage is divided into three groups: Stage 3A, Stage 3B, and Stage 3C. The difference is determined by the size of the tumor and whether cancer has spread to the lymph nodes and surrounding tissue.
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Stage 2 Cancer Treatment Options
In general, stage 2 cancers tend to be treated locally with surgery and/or radiation. At times, chemotherapy or other drug therapies may also be a part of stage 2 cancer treatment. Below, find stage 2 cancer treatment options for the five most common cancers.
Stage 2 breast cancer treatment: Stage 2 breast cancer tends to be most commonly treated with surgerya lumpectomy or mastectomyand radiation treatment afterward. During the surgery, doctors check the nearby lymph nodes for cancer, too. Most patients also have medication as part of their treatment plan: either chemotherapy, breast cancer targeted therapy, hormone therapy or a combination.
Stage 2 lung cancer treatment: Stage 2 lung cancer is typically treated with surgery. Some people may also have chemotherapy after surgery. For patients who cant have surgery, radiation may be a treatment option.
Stage 2 prostate cancer treatment: For stage 2 prostate cancer, treatment depends on the patients symptoms, age and overall health. If the patient is older and isnt experiencing symptoms, doctors may simply keep an eye on how the tumor is doing and treat it if theres any drastic change. However, stage 2 cancers are more likely to spread without treatment than stage 1 cancers. Treatment options may include surgery, surgery followed by radiation, radiation only, or radiation with hormone therapy.
Expert
Hormone Receptor Status Can Influence Survival Rates
When a breast cancer tumor is sent for histological analysis, one of the characteristics of the report will be the hormone receptor status of the tumor.
Estrogen receptor and progesterone receptor positive tumors tend to respond better to chemotherapy. Chemotherapy tends to be the treatment of choice for stage III and IV breast cancers.
Breast cancers which are triple negative tend to have the least favourable survival rates, regardless of breast cancer stage.
One 2011 research study looked at 269 triple-negative breast cancer patients all treated at the same institution between 2000 and 2006.
This study found that the average age at diagnosis was 55.3 years. The 5 year disease-free survival rate for the whole group was 68.2%. However, the 5 year overall survival rate for the entire group was higher at 74.5%.
Risk of recurrence was higher in the first 3 years following the initial diagnosis. However, the recurrence rate declined significantly after this initial 3 year period.
Other factors that were found to be important factors on survival rates were:-
- Lymph node status
- Lymphovascular invasion
- Age: Ladies older than 65 years had a poorer prognosis
However, ER and PR status tends to have more of an influence on survival than HER2 status. Patients with ER+/PR+/HER2- subtype of breast cancer have an estimated 5-year survival rate of 87.8%.
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Can Stage 4 Breast Cancer Go Into Remission
Stage 4 breast cancer can go into remission, meaning that it isnt detected in imaging or other tests. Pathological complete remission indicates a lack of cancer cells in tissues removed after surgery or biopsy.
But its rare to take tissue samples while treating stage 4 breast cancer. This could mean that although treatment has been effective, it hasnt completely destroyed the cancer.
Advances in stage 4 breast cancer treatments are helping to increase the length of remission.
Prognosis And Survival For Breast Cancer
If you have breast cancer, you may have questions about your prognosis. A prognosis is the doctors best estimate of how cancer will affect someone and how it will respond to treatment. Prognosis and survival depend on many factors. Only a doctor familiar with your medical history, the type, stage and characteristics of your cancer, the treatments chosen and the response to treatment can put all of this information together with survival statistics to arrive at a prognosis.
A prognostic factor is an aspect of the cancer or a characteristic of the person that the doctor will consider when making a prognosis. A predictive factor influences how a cancer will respond to a certain treatment. Prognostic and predictive factors are often discussed together. They both play a part in deciding on a treatment plan and a prognosis.
Doctors use different prognostic and predictive factors for newly diagnosed and recurrent breast cancers.
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Clinical Manifestations Of Stage 4
The main classification signs of breast cancer stage 4 are its spread to remote organs or lymph nodes. The size of the tumor at this stage is no longer important moreover, it may no longer be detected at the primary site.
It is the metastases that most often develop in the liver, lungs, and bones that give information about the development of the oncological process. They are painful and cause vivid symptoms. Metastases in the liver give jaundice and increase abdominal size. Metastases in the lungs give shortness of breath, and in the bones severe pain and frequent fractures.
- severe intoxication
Checking The Lymph Nodes
The usual treatment is surgery to remove the cancer. Before your surgery you have an ultrasound scan to check the lymph nodes in the armpit close to the breast. This is to see if they contain cancer cells. If breast cancer spreads, it usually first spreads to the lymph nodes close to the breast.
Depending on the results of your scan you might have:
- a sentinel lymph node biopsy during your breast cancer operation
- surgery to remove your lymph nodes
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Survival Rates For Stage Iv Breast Cancer
Stage of breast cancer at diagnosis is one of the most important prognostic factors. Above is a bar chart from the National Cancer Institute statistics for 2012. As we can see, the 5-year survival rate for women diagnosed with Stage IV breast cancer was 22%.
Remember, these figures are still quite dated as it takes 5 years to determine survival rates and treatment is improving all the time.
A recent study found that 37% of women survived for three years after a Stage IV breast cancer diagnosis, although some women do survive longer.
However, although the 5-year survival rates are much higher for earlier stages of breast cancer at diagnosis, there is no predicting which cases will progress to metastatic breast cancer in the future.
Although it is important to be realistic regarding the survival of metastatic breast cancer, each individual situation is unique and ultimately, statistics are meaningless.
There is a small subcategory of people with Stage IV breast cancer who beat the odds and live for years. However, it is difficult to predict who will fall into this group.
All that is known is that people in this group have secondary spread to the bones. Furthermore, cancer is often estrogen positive and responds to hormone treatments.
Triple Negative Breast Cancer
With this type of breast cancer, the breast cancer cells dont have ER+ or PR+ receptors. They dont overproduce the HER2 protein, so hormone therapy isnt very effective.
Instead, triple negative stage 4 breast cancer is usually treated with chemotherapy. Radiation therapy may also be an option, depending on the site of metastasis.
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More Information About The Tnm Staging System
The T category describes the original tumor:
- TX means the tumor can’t be assessed.
- T0 means there isn’t any evidence of the primary tumor.
- Tis means the cancer is “in situ” .
- T1, T2, T3, T4: These numbers are based on the size of the tumor and the extent to which it has grown into neighboring breast tissue. The higher the T number, the larger the tumor and/or the more it may have grown into the breast tissue.
The N category describes whether or not the cancer has reached nearby lymph nodes:
- NX means the nearby lymph nodes can’t be assessed, for example, if they were previously removed.
- N0 means nearby lymph nodes do not contain cancer.
- N1, N2, N3: These numbers are based on the number of lymph nodes involved and how much cancer is found in them. The higher the N number, the greater the extent of the lymph node involvement.
The M category tells whether or not there is evidence that the cancer has traveled to other parts of the body:
- MX means metastasis can’t be assessed.
- M0 means there is no distant metastasis.
- M1 means that distant metastasis is present.
Survival Rates For Breast Cancer
Survival rates can give you an idea of what percentage of people with the same type and stage of cancer are still alive a certain amount of time after they were diagnosed. They cant tell you how long you will live, but they may help give you a better understanding of how likely it is that your treatment will be successful.
Keep in mind that survival rates are estimates and are often based on previous outcomes of large numbers of people who had a specific cancer, but they cant predict what will happen in any particular persons case. These statistics can be confusing and may lead you to have more questions. Talk with your doctor about how these numbers may apply to you, as he or she is familiar with your situation.
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Mortality Rates Versus Number Of Breast Cancer Deaths
Sometimes its useful to have an estimate of the number of people expected to die from breast cancer in a year. This numbers helps show the burden of breast cancer in a group of people.
Numbers, however, can be hard to compare to each other. To compare mortality rates in different populations, we need to look at mortality rates rather than the number of breast cancer deaths.
The Types Of Radiotherapy
The type of radiotherapy you have will depend on the type of breast cancer and the type of surgery you have. Some women may not need to have radiotherapy at all.
Types of radiotherapy include:
- breast radiotherapy after breast-conserving surgery, radiation is applied to the whole of the remaining breast tissue
- chest-wall radiotherapy after a mastectomy, radiotherapy is applied to the chest wall
- breast boost some women may be offered a boost of high-dose radiotherapy in the area where the cancer was removed however, this may affect the appearance of your breast, particularly if you have large breasts, and can sometimes have other side effects, including hardening of breast tissue
- radiotherapy to the lymph nodes where radiotherapy is aimed at the armpit and the surrounding area to kill any cancer that may be in the lymph nodes
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Is Stage 4 Breast Cancer Curable
Theres currently no cure for stage 4 breast cancer, but with treatments it can be kept under control, often for years at a time.
People with metastatic breast cancer need to receive treatments for the rest of their lives. If a certain treatment stops being effective, another treatment regimen may be tried.
Examples Using The Full Staging System
Because there are so many factors that go into stage grouping for breast cancer, it’s not possible to describe here every combination that might be included in each stage. The many different possible combinations mean that two women who have the same stage of breast cancer might have different factors that make up their stage.
Here are 3 examples of how all of the factors listed above are used to determine the pathologic breast cancer stage:
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Symptoms Of Metastatic Breast Cancer
The symptoms of stage 4 breast cancer depend on the location of the cancer and where it has spread in your body.
- If breast cancer has spread to your bones, you may notice a sudden new bone pain. Breast cancer most commonly spreads to your ribs, spine, pelvis, or arm and leg bones.
- If it has spread to your brain, you may experience headaches, vision or speech changes, or memory problems.
- Breast cancer that has spread to your lungs or liver usually causes no symptoms.
The main treatments for stage 4 breast cancer are targeted drug therapies that destroy cancer cells wherever they are in your body.
These treatments may include:
- hormone therapy, which stops or slows the growth of tumors by preventing your body from producing hormones or interfering with the effect of hormones on breast cancer cells
- chemotherapy, where drugs given orally or through an IV travel through your bloodstream to fight cancer cells
- immunotherapy, which uses drugs that stimulate your immune system to destroy cancer cells
- a combination of these therapies
In some cases, surgery or radiation therapy may be used to treat stage 4 breast cancer.
The following are the common treatment options for different types of stage 4 breast cancer.