Breast Cancer As A Brand
Breast cancer advocacy uses the pink ribbon and the color pink as a concept brand to raise money and increase screening. The breast cancer brand is strong: people who support the “pink brand” are members of the socially awareniche market, who are in favor of improved lives for women, believe in positive thinking, trust biomedical science to be able to solve any problem if given enough money, and prefer curative treatments to prevention.
The brand ties together fear of cancer, hope for early identification and successful treatment, and the moral goodness of women with breast cancer and anyone who visibly identifies themselves with breast cancer patients. This brand permits and even encourages people to substitute conscientious consumption and individual symbolic actions, like buying or wearing a pink ribbon, for concrete, practical results, such as collective political action aimed at discovering non-genetic causes of breast cancer.
The establishment of the brand and the entrenchment of the breast cancer movement has been uniquely successful, because no countermovement opposes the breast cancer movement or believes that breast cancer is desirable.
Assessment Of Coffee Consumption
Coffee consumption was self-reported on the 1999 survey using a 152-item modified Harvard food frequency questionnaire . Usual intake of one cup of caffeinated and decaffeinated coffee over the previous year was reported in one of 10 possible frequencies ranging from never to 6 per day. Participants who left either type of coffee blank , or whose reported consumption was never or < once per month were assigned 0 cups per day. Average cups of total coffee were calculated by summing the contribution from each type categories were nondrinker , < 1 cup/day, 1< 2 cups/day, and 2 cups/day.
Rally In Supporting Everyone
Behind every photo is a story with the power to uplift and inspire others. Tell us how you or a loved one has been impacted by breast cancer.Well share your stories throughout the month of October in celebration of the ways we RISE together and as a message of hope for others on their own breast cancer journey.
Every Dollar Matters
Whether youre funding a mammogram, supporting education, or helping reach women in underserved communities, your donation matters. Click the button below to select how your contribution will be used.
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Risk Factors You Can Control
According to the American Cancer Society, personal behaviors, such as diet and exercise, do affect cancer risk. The following three lifestyle factors are considered risk factors for breast cancer:
- Drinking alcohol The risk of breast cancer increases with the amount of alcohol consumed. For women who drink, it is best to limit alcohol to less than one drink per week.
- Being overweight or obese, especially after menopause The American Cancer Society recommends balancing your weight throughout life by balancing calories with physical activity.
- Lack of physical activity, especially after menopause There is growing evidence that exercise lowers breast cancer after menopause.
Breast Cancer Awareness Month : Importance Of Early Detection
According to studies, early detection of breast cancer can increase the survival rates of the patient. It is important to check for the signs and symptoms of breast cancer. Symptoms may include- presence of lump in the breast, pain in the breast, swelling in areas near the breasts, discharge from nipple other than breast milk, change in the shape of the nipple and swelling under arm. In some cases, these may not be the sign of breast cancer but any of these signs should be reported to the doctor immediately.
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Breast Cancer During The Covid
In the COVID-19 pandemic triggered by the Severe Acute-Respiratory Syndrome Coronavirus type-2 , cancer patients constitute a special risk group, with the pandemic having implications in all areas of care and treatment of, e.g., breast cancer. Between March and April 2020, 23.8% fewer breast cancer cases were treated in German hospitals compared to the same period the previous year. It is possible that the pandemic has resulted in reduced oncological care, because cancer surgery had to be postponed or even cancelled altogether. The professional societies DGHO , ESMO, ASCO, and others have developed guidelines and recommendations for the management and prioritisation of treatment interventions in breast cancer during the COVID pandemic,,,,.
DEfenseCOVID-19 Registration process and study workflow.
Einfluss Von Ernhrung Und Mikrobiom Auf Das Brustkrebsrisiko
Das Mikrobiom des Darms wurde bereits in der Vergangenheit mit der Wirksamkeit von Immuntherapien für Krebspatienten in Verbindung gebracht. Nun wurde auch der Zusammenhang zwischen Darmmikrobiom und Brustkrebsrisiko untersuchtwobei auf eine bestehende große Fallkontrollstudie mit mehr als 130000 Brustkrebsfällen und mehr als 110000 Kontrollen zurückgegriffen wurde. Weiterhin wurden Studien berücksichtigt, welche die Assoziation von genetischen Varianten und dem Auftreten von spezifischen Mikrobiommustern untersucht hatten. Die 13 genetischen Varianten, die mit spezifischen Mikrobiommustern assoziiert waren, wurden dann in der großen Fallkontrollstudiemittels Mendelscher Randomisierung auf eine Assoziation mit dem Brustkrebsrisiko untersucht. Inder Gesamtpopulation wurden Bakterien der Art Genus Ruminococcus als Risikofaktor identifiziert. Für das triple-negative Mammakarzinom wurden Bakterien der Gattung G. Parabacteroides als protektiv und unklassifizierte Bacteroidales-Bakterien als Risikofaktoren identifiziert. Da die Zusammenhänge zwischen Gesundheit und dem Mikrobiom noch nicht vollständig geklärt sind, ist es jedoch schwierig, eine risikoreduzierende Intervention anhand dieser Daten zu etablieren.
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Environmental Breast Cancer Movement
Most of the money raised by advocates is spent on increasing awareness, cancer screening, and existing treatments. Only a small fraction of the funds is spent on research, and less than 7% of the total research funding provided by breast cancer organizations goes to prevention. Instead, most of the charities fund research into detection and treatment. Advocates like Breast Cancer Action and women’s health issues scholar Samantha King, whose book inspired the 2011 documentary Pink Ribbons, Inc., are unhappy that relatively little money or attention is devoted to identifying the non-genetic causes of breast cancer or to preventing breast cancer from occurring. The mainstream breast cancer culture has been criticized for focusing on detecting and curing existing breast cancer cases, rather than on preventing future cases.
As a result, screening mammography is promoted by the breast cancer culture as the sole possible approach to public health for breast cancer. Alternatives, such as pollution prevention, are largely ignored.
Samantha King says that prevention research is minimized by the breast cancer industry because there is no way to make money off of cases of breast cancer that do not happen, whereas a mammography imaging system that finds more possible cancers, or a “magic bullet” that kills confirmed cancers, would be highly profitable.
Impact Of Diet And Microbiome On Breast Cancer Risk
In the past, the gut microbiome has already been linked to the efficacy of immunotherapy in cancer patients. The association between gut microbiome and breast cancer risk has also been studiedby now based on an existing large case-control study of over 130000 breast cancer cases and more than 110000 controls. Moreover, studies were included that had investigated the correlation between genetic variants and the presence of specific microbiome patterns. The 13 genetic variants correlating with specific microbiome patternswere then studied by Mendelian randomisation for their correlation with breast cancer risk in the large case-control study. In the overall population, the bacterialgenus ruminococcuswas identified as a risk factor. Intriple-negative breast cancer , bacteria of thegenus parabacteroideshave been identified as protective and unclassified bacteria of theorder bacteroidalesas risk factors. However, as the interaction between health and the microbiome is not yet fully understood, it is difficult to establish a risk-reducing interventional strategy based on this data.
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Survival Analysis Update Of The Keynote
The data from the third interim analysis of the KEYNOTE-522 trial was presented at a meeting of the Oncologic Drugs Advisory Committee at the US Food and Drug Administration . This analysis was based on a total of 174 events. The hazard ratio was 0.65 . However, because of the numerous interim analyses, the p-value should have been 0.0021. Thus, the difference was not statistically significant. The corresponding Kaplan-Meier graph is shown in. Interestingly enough, the analysis regarding pCR was also repeated. While 602 patients participated in the initial analysis , now all 1174 patients in the intention-to-treat population participated. The pCR rate in the chemotherapy arm was 55.6% and in the pembrolizumab+chemotherapy arm 63.0%. So the difference was only 7.5%.
Kaplan-Meier estimator for event-free survival in the KEYNOTE-522 trial at the third interim analysis .
Breast Cancer Awareness Month 2020
Breast Cancer Awareness Month is a worldwide, annual campaign that highlights the importance of breast cancer awareness, education, and research. About 1 in 8 U.S. women will develop invasive breast cancer over the course of her lifetime. For men, the lifetime risk of being diagnosed with breast cancer is about 1 in 833 .
PartnerMD is doing our part to help. All month, we’ll be sharing articles, posting on social media, and sharing wellness videos from our health coaches to help you reduce your risk for breast cancer. Find links to all of our content below.
All this activity culminated in “A PMD Conversation: Breast Cancer” on Thursday, October 29. Dr. Steven Bishop, Dr. Tamara Sobel, and Dr. Susan Scharpf discussed breast cancer prevention, screening, diagnosis, anxiety, and more. Find the video and recap here.
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Prevention Week Has Begun
They say prevention is better than cure but all too often these days the concept of prevention is overlooked.So we want to make some noise about Prevention and all of the benefits it can bring.
Thanks to breast cancer awareness month we are all now far more aware of breast cancer its symptoms, self-checking etc.
But the truth is, we are also far more aware of breast cancer today quite simply because most of us know someone who has got it or who has had it.
1 in 8 women in the UK will be diagnosed with breast cancer at some point in their lives.1 in 5 of these cases will be in women under the age of 50.Although less common, around 350 men are diagnosed with breast cancer every year.
Whilst improved methods of detection and treatment are vital, we must also look at how we can help to prevent breast cancer it should not be considered to be an inevitable, disease.
Breast Cancer UK believes prevention is possible.
Thats why we are launching our first ever Prevention week today!
A week long shout out about the benefits of prevention, along with helpful tips and ideas on how you can help reduce your risk of breast cancer.
Throughout the week we will be posting inspiring blogs from a range of opinion formers, policy makers and health campaigners including Sir Tim Smit KBE , Sharon Hodgson MP , Kerry McCarthy MP and Janey Lee Grace .
A full round up of whats happening this week can be found here
Prognostic Models For Patients After Neoadjuvant Chemotherapy
Pathologic complete response is an excellent predictor of prognosis post neoadjuvant chemotherapy, especially in patients with TNBC or HER2+ breast cancer,,,,. However, for patients without pCR and even for a few patients with pCR, there could be significant differences in prognosis. A number of papers have addressed this issue. The simplest approach is to follow the AJCC staging criteria, which can be used to classify patients into different prognostic groups after neoadjuvant chemotherapy.
These predictions can be improved by two additional models:
The CPS-EG score was developed precisely for this purpose,and was also used in the PENELOPE-B trial as a predictive parameter for prognosis. Later, the CPS-EG score was refined into the Neo-Bioscore. CPS-EG and Neo-Bioscore assign certain tumour characteristics before and after chemotherapy to arbitrary points, which are summed up to a total . These different scores may result in better prognostic prediction than the AJCC criteria alone,,,. The continuously calculated residual cancer burden represents another tool for predicting patient prognosis following neoadjuvant chemotherapy. Residual tumour diameter, percentage of residualcancer cells, percentage of in situ tumour parts, number of affected lymph nodes, and the largest diameter of an affected lymph node together are all entered into a regression model to calculate the RCB, which is then categorised into 4 RCB classes: RCB-0 , RCB-I: , RCB-II and RCB-III .
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How To Raise Awareness For Breast Cancer Awareness Month
Every October, people all over the world show their support for everyone affected by breast cancer. Were focused on accelerating research and providing vital support, every way we can no matter who you are or what your experience of this disease may be like. This month is Breast Cancer Awareness Month now more than ever its important that those who have been impacted know theyre not alone in fighting these battles!
- Learn the Signs and symptoms to be aware of after primary breast cancer https://breastcancernow.org/information-support/signs-symptoms-be-aware-after-primary-breast-cancer
- Raise awareness of breast cancer in men https://breastcancernow.org/information-support/have-i-got-breast-cancer/breast-cancer-in-men
Breast Cancer Prevention Patient Version
On This Page
Cancerprevention is action taken to lower the chance of getting cancer. By preventing cancer, the number of new cases of cancer in a group or population is lowered. Hopefully, this will reduce the burden of cancer and lower the number of deaths caused by cancer.
Cancer is not a single disease but a group of related diseases. Our genes, lifestyle, and the environment around us work together to increase or decrease our risk of getting cancer. Each persons cancer risk is made up of a combination of these factors.
Some risk factors for cancer can be avoided, but many cannot. Forexample, both smoking and inheriting certain genes are risk factors for sometypes of cancer, but only smoking can be avoided. Regular exercise and a healthy diet may be protective factors for some types of cancer. Avoiding risk factors and increasing protective factors may lower your risk but it doesnot mean that you will not get cancer.
Different ways to prevent cancer are being studied, including:
- Changing lifestyle or eating habits.
- Avoiding things known to cause cancer.
- Taking medicine to treat a precancerouscondition or to keep cancer from starting.
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Neoadjuvante Therapie Bei Patientinnen Mit Hormonrezeptorpositiven Her2
Obwohl eine pathologische Komplettremission generell eine gute Prognose nach einer neoadjuvanten Chemotherapie vorhersagt, ist dieser Effekt bei Patientinnen mit einem HER2-positiven oder TNBC am deutlichsten,,,,. Bei Patientinnen mit HR+ HER2 Tumoren ist der Zusammenhang weniger deutlich, weswegen das Verständnis für Resistenzmechanismen in der neoadjuvanten Situation von besonderer klinischer Relevanz ist. Eine wichtige klinische Fragestellung ist, ob bei endokriner Resistenz oder endokriner Sensitivität eine Chemotherapie mit einem Benefit assoziiert ist. Ki-67 und Multigen-Tests scheinen in dem Zusammenhang vielversprechende Biomarker zu sein. Das Ansprechen auf eine endokrine Therapie im Sinne einer Ki-67-Reduktion innerhalb weniger Wochen war ein aussagekräftigerPrognosemarker z.B. in der POETIC-Studie.
It Is Not Clear Whether The Following Affect The Risk Of Breast Cancer:
Hormonal contraceptives contain estrogen or estrogen and progestin. Some studies have shown that women who are current or recent users of hormonal contraceptives may have a slight increase in breast cancer risk. Other studies have not shown an increased risk of breast cancer in women using hormonal contraceptives.
In one study, the risk of breast cancer slightly increased the longer a woman used hormonal contraceptives. Another study showed that the slight increase in breast cancer risk decreased over time when women stopped using hormonal contraceptives.
More studies are needed to know whether hormonal contraceptives affect a woman’s risk of breast cancer.
Chemicals in the environment
These reasons make it hard to know which chemicals, if any, may increase the risk of breast cancer. More studies are needed to know whether chemicals in the environment affect a woman’s risk of breast cancer. For more information, see Environmental Carcinogens and Cancer Risk.
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Panel Gene Knowledge Deepens
Lifetime risk up to 80 years of age for the eight confirmed risk genes according to.
Table 1The risk genes studied in over 60000 breast cancer patients and more than 53400 healthy controls.
|1Breast cancer risk correlation with a p-value < 0.00012Breast cancer risk correlation with a p- value < 0.05bold = confirmed breast cancer risk genes with high or moderate penetrance|
Avoiding Risk Factors And Increasing Protective Factors May Help Prevent Cancer
Avoiding cancerrisk factors may help prevent certain cancers. Risk factors include smoking, being overweight, and not getting enough exercise. Increasing protective factors such as quitting smoking and exercising may also help prevent some cancers. Talk to your doctor or other health care professional about how you might lower your risk of cancer.
NCI’sBreast Cancer Risk Assessment Tool uses a woman’s risk factors to estimate her risk for breast cancer during the next five years and up to age 90. This online tool is meant to be used by a health care provider. For more information on breast cancer risk, call 1-800-4-CANCER.
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