In Situ Vs Invasive Breast Cancers
The type of breast cancer can also refer to whether the cancer has spread or not. In situ breast cancer is a cancer that starts in a milk duct and has not grown into the rest of the breast tissue. The term invasive breast cancer is used to describe any type of breast cancer that has spread into the surrounding breast tissue.
Invasive breast cancer has spread into surrounding breast tissue. The most common types are invasive ductal carcinoma and invasive lobular carcinoma. Invasive ductal carcinoma makes up about 70-80% of all breast cancers.
How To Detect Types Of Cancer In Women: 8 Common Cancers Symptoms And Treatments
A disease that can rapidly develop mainly due to the abnormal multiplication of the cells within the body is considered cancer. Due to many reasons that include genetic mutations, habits, and lifestyle that includes smoking and drinking, infections that are viral in nature, obesity, and chronic inflammation can develop significantly. Irrespective of the gender here, along with age, cancer can duly affect anyone. However, among women from around the globe, there are a few cancers that are quite prevalent.
Infiltrating/invasive Lobular Breast Carcinoma
Infiltrating lobular carcinoma usually appears as a subtle thickening in the upper-outer breast quadrant.
As the name suggests, these tumours originate mostly in the breast lobules rather than the lining of the breast ducts.
Invasive lobular cancer is a less common type of breast cancer than invasive ductal cancer. This cancer accounts for about 10% of all invasive breast cancer cases.
Prognosis for infiltrating and invasive lobular breast carcinomas will naturally be influenced by tumor size, grade, stage and hormone receptor status..
However, lobular breast cancers, when positive for estrogen and progesterone receptors, tend to respond very well to hormone therapy.
The overall breast cancer survival rates for infiltrating lobular carcinoma, when matched by stage, are a little higher than for ductal carcinoma for the first 5 years.
Survival rates range from about 77% to 93%, but on average, the 5-year survival rate was estimated at about 90%.
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Breast Cancer Type’ Is Determined By Cell Shape And Appearance
Breast cancers or carcinomas are mainly of epithelial cell origin.
Epithelial cells are the lining of most of our organs and vessels.
However, there are quite a few very rare types of breast cancers which are comprised of non-epithelial cells . Furthermore, a great many breast cancers are actually not pure, but rather a mixture of different types of cells.
In general, there are six types of standard breast carcinomas, and statistically, some of these tend to show a better prognosis than others.
The six most common types of breast cancer are as follows:-
Special Types Of Invasive Breast Cancers
Some invasive breast cancers have special features or develop in different ways that affect their treatment and outlook. These cancers are less common but can be more serious than other types of breast cancer.
Inflammatory breast cancer is an uncommon type of invasive breast cancer. It accounts for about 1% to 5% of all breast cancers.
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Breast Cancer Survival Rates According To The Stage Of The Cancer
Breast cancer stage of course refers to the spread and size of cancer at diagnosis. Stage zero means the breast cancer is still in situ or contained. Whereas, stage IV means that the cancer has metastasised to other body regions. The stage of cancer at diagnosis affects prognosis.
The statistics below are taken from the from the SEER database of the National Cancer Institute between the years 1975 to 2010.
The 5 year survival rate means that within 5 years around 93 people out of 100, diagnosed with Stage II breast cancer, will still be alive.
What Are The Warning Signs Of Breast Cancer
- A lump or thickening in or near the breast or in the underarm that persists through the menstrual cycle.
- A mass or lump, which may feel as small as a pea.
- A change in the size, shape, or contour of the breast.
- A blood-stained or clear fluid discharge from the nipple.
- A change in the look or feel of the skin on the breast or nipple .
- Redness of the skin on the breast or nipple.
- An area that is distinctly different from any other area on either breast.
- A marble-like hardened area under the skin.
These changes may be found when performing monthly breast self-exams. By performing breast self-exams, you can become familiar with the normal monthly changes in your breasts.
Breast self-examination should be performed at the same time each month, three to five days after your menstrual period ends. If you have stopped menstruating, perform the exam on the same day of each month.
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Can Exercise Help Reduce My Risk Of Developing Breast Cancer
Exercise is a big part of a healthy lifestyle. It can also be a useful way to reduce your risk of developing breast cancer in your postmenopausal years. Women often gain weight and body fat during menopause. People with higher amounts of body fat can be at a higher risk of breast cancer. However, by reducing your body fat through exercise, you may be able to lower your risk of developing breast cancer.
The general recommendation for regular exercise is about 150 minutes each week. This would mean that you work out for about 30 minutes, five days each week. However, doubling the amount of weekly exercise to 300 minutes can greatly benefit postmenopausal women. The longer duration of exercise allows for you to burn more fat and improve your heart and lung function.
The type of exercise you do can vary the main goal is get your heart rate up as you exercise. Its recommended that your heart rate is raised about 65 to 75% of your maximum heart rate during exercise. You can figure out your maximum heart rate by subtracting your current age from 220. If you are 65, for example, your maximum heart rate is 155.
Aerobic exercise is a great way to improve your heart and lung function, as well as burn fat. Some aerobic exercises you can try include:
Remember, there are many benefits to working more exercise into your weekly routine. Some benefits of aerobic exercise can include:
Risk Factors For Breast Cancer
There are several risk factors that increase your chances of getting breast cancer. However, having any of these doesnt mean you will definitely develop the disease.
Some risk factors cant be avoided, such as family history. You can change other risk factors, such as quitting smoking, if you smoke. Risk factors for breast cancer include:
While there are risk factors you cant control, following a healthy lifestyle, getting regular screenings, and taking any preventive measures your doctor recommends can help reduce your risk for developing breast cancer.
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Breast Exam By Your Doctor
The same guidelines for self-exams provided above are true for breast exams done by your doctor or other healthcare professional. They wont hurt you, and your doctor may do a breast exam during your annual visit.
If youre having symptoms that concern you, its a good idea to have your doctor do a breast exam. During the exam, your doctor will check both of your breasts for abnormal spots or signs of breast cancer.
Your doctor may also check other parts of your body to see if the symptoms youre having could be related to another condition.
Committee For Missing Children
Like Operation Lookout National Center for Missing Youth, the next entry to our list reports to help return missing children to the parents arms. In reality, only 2% of donations go towards the cause. The rest, funnily enough, somewhere makes it into the likes of director David Thelens pockets. Thelen may defend his excessive salary by claiming to spend endless hours counseling the families of the missing children, but we doubt theyll be very thankful when they find out how little practical effort the charity puts into finding their kids.
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Mortality Rates Versus Number Of Breast Cancer Deaths
Sometimes its useful to have an estimate of the number of people expected to die from breast cancer in a year. This numbers helps show the burden of breast cancer in a group of people.
Numbers, however, can be hard to compare to each other. To compare mortality in different populations, we need to look at mortality rates rather than the number of breast cancer deaths.
Cancer Fund Of America
Cancer Fund of America is just one of many philanthropic centers run by James T Reynolds and his somewhat crooked family. That the no-shame Reynolds takes home an annual salary of around $230,000 is bad enough . That the charity only manages to find it in its heart to give 2.5% of its donations to support the families of cancer victims and fund cancer research is even worse. If you want to subsidize the flash lifestyle of Reynolds, then go right ahead and donate. If youd rather your money found its way into the pockets of who it should, then maybe find yourself a better cause.
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What Is The Stage Of My Cancer
Cancer staging is a standardized way of classifying the severity of a patients cancer. There are various systems that use number or letter codes to designate the cancers status and how far it may have spread.
You may have heard of Stages 0 through IV, which reflect a tumors size and the extent of metastasis. A higher stage means a larger tumor and wider distribution of cancer cells.
Your doctor uses staging to plan your treatment, gauge your prognosis and communicate with other cancer specialists. What stage your cancer is in also will help determine whether youre eligible for clinical trials which offer newer treatment options.
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Breast Cancer Relief Foundation
Whether the Breast Cancer Relief Foundation is immoral or just extremely incompetent, were a bit unsure. What we are sure of is that of the millions of dollars its claims to send in medical supplies to developing nations, theres very little trace. Neither is there very much money making its way into cancer research, with only 2% of its donations ending up helping women with breast cancer.
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Age At The Time Of Diagnosis Affects Breast Cancer Survival Rates
It has always been known that curiously, young women have a poorer prognosis than older ones
Indeed, one cohort study examined 4,453 women with breast cancer between 1961 and 1991 who were all treated at the same center.
This study found that both ends of the age spectrum fared less well. So, women under the age of 40 years at diagnosis and those over 80 years had a statistically poorer prognosis.
However, for younger women, this may be due to the fact that they often present with higher-grade tumors that tend to be more aggressive and less likely to be hormone receptor-positive. This means that breast cancer may not respond as well to treatment.
So, it is important to bear in mind other factors discussed in this post, such as stage, grade and hormone receptor status play an important role in prognosis.
Tnm System For Breast Cancer
Doctors also group cancers by the letters T, N, or M. Each of those letters tells you something about your cancer.
âTâ stands for tumor, or the lump of cancer found in the breast itself. The higher the number assigned after it, the bigger or wider the mass.
âNâ stands for nodes, as in lymph nodes. These small filters are found throughout the body, and they’re especially dense in and around the breast. They’re meant to catch cancer cells before they travel to other parts of the body. Here, too, a number tells you whether the cancer has spread to lymph nodes near the breast and, if so, how many.
âMâ stands for metastasis. The cancer has spread beyond the breast and lymph nodes.
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The Precuneus And Its Neighbors
Although a relatively unstudied area of the brain, the precuneus role appears to be an important one. The precuneus and surrounding areas have the highest resting metabolic rates in the brain a sure sign that they have a lot of work to do.
It is thought to play a role in a number of integrated tasks, including visuospatial imagery and the retrieval of episodic memories.
Connections between the precuneus and the frontal, hippocampal and lateral parietal regions were found to be lacking in the anthracycline-based groups brains. This lack of linkage is thought to disrupt the efficiency of information processing and lessen dynamic responses in cognitive tasks.
As for the mechanisms at work in degenerating connectivity in these specific brain regions, that is up for debate. One theory involves cytokines. Anthracycline-based chemotherapy has been found to release more proinflammatory cytokines, causing increased neuroinflammation that may be to blame.
Another avenue of interest might be the effects of oxidative stress on the brain. Chemotherapy has been found to produce reactive oxygen species and, at the same time, reduce the patients ability to react and clear the destructive agents. This could lead to direct damage of the neurons.
The authors conclude:
Chemotherapy, its effectiveness and its consequences are rightfully under constant scrutiny. With time, no doubt, the chemobrain phenomenon will become well understood and preventable.
The 10 Deadliest Cancers And Why There’s No Cure
ByAmanda Chan10 September 2010
The dread and fear that can come with a cancer diagnosis have their roots in its killer nature: It’s the No. 2 cause of death in Americans, second only to heart disease, according to the Centers for Disease Control and Prevention. Even when diagnosed early and attacked with the latest treatments, it still has the power to kill.
To help raise money to find cures and treatments for cancer patients, the “Stand Up to Cancer” telethon will air on ABC, NBC and CBS and other networks and cable stations starting at 8 p.m. ET tonight. The telethon will feature a host of celebrity guests, including George Clooney, Denzel Washington, Renee Zellweger and Will Smith.
“‘Stand Up To Cancer’ represents collaborative efforts” to provide funding for cancer research, Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society, told MyHealthNewsDaily.
“We would not be where we are if basic and clinical science wasn’t funded,” Lichtenfeld said. “Basic science teaches us about mechanisms, about how drugs may be effective, and we take that info and put it into a clinic to find out whether or not those new ideas work in cancer treatment.”
Cancer cells, and how they grow, remain unpredictable and in some cases mysterious. Even after seemingly effective treatments, crafty cancer cells are able to hide out in some patients and resurface.
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Survival And Mortality Rates
Survival depends on mortality. You start with 100 percent of the people in the group.
100 percent mortality rate = survival rate
Say, the mortality rate in the group of people is 5 percent. Survival would be 95 percent .
Similarly, the number of people in a group who survive depends on the number of people who die. Say, 500 people are in the group and 1 person dies. This means 499 people survived .
Association For Firefighters And Paramedics
Deceptive fundraising ploys, improper allocation of funds, investigations by state authorities if there was a checklist of what makes a charity less than reputable, the Association for Firefighters and Paramedics would tick every box. Unless you want your donation to fund the lavish lifestyles of the charitys top execs, do yourself a favor and keep your money in your wallet.
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Basal Type Breast Cancer
Basal type breast cancer has particular genetic changes in the cells. The cells make large amounts of a protein called cytokeratin 5/6.
Basal type breast cancers are often triple negative. This means that they don’t have many receptors for oestrogen, progesterone, or HER2. So, hormone therapies and targeted drugs don’t work for most basal type cancers.
Doctors use other treatments, such as surgery, chemotherapy and radiotherapy, instead.
How Can I Protect Myself From Breast Cancer
Follow these three steps for early detection:
- Get a mammogram. The American Cancer Society recommends having a baseline mammogram at age 35, and a screening mammogram every year after age 40. Mammograms are an important part of your health history. Recently, the US Preventive Services Task Force came out with new recommendations regarding when and how often one should have mammograms. These include starting at age 50 and having them every two years. We do not agree with this, but we are in agreement with the American Cancer Society and have not changed our guidelines, which recommend yearly mammograms starting at age 40.
- Examine your breasts each month after age 20. You will become familiar with the contours and feel of your breasts and will be more alert to changes.
- Have your breast examined by a healthcare provider at least once every three years after age 20, and every year after age 40. Clinical breast exams can detect lumps that may not be detected by mammogram.
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