Tuesday, September 27, 2022
HomeWhat Leads To Breast Cancer

What Leads To Breast Cancer

Can Cancer Form In Other Parts Of The Breast

3D Mammogram Leads to Breast Cancer Discovery

Cancers can also form in other parts of the breast, but these types of cancer are less common. These can include:

  • Angiosarcomas. This type of cancer begins in the cells that make up the lining of blood or lymph vessels. These cancers can start in breast tissue or breast skin. They are rare.
  • Inflammatory breast cancer. This type of cancer is rare and different from other types of breast cancer. It is caused by obstructive cancer cells in the skins lymph vessels.
  • Paget disease of the breast, also known as Paget disease of the nipple. This cancer affects the skin of the nipple and areola .
  • Phyllodes tumors. These are rare, and most of these masses are not cancer. However, some are cancerous. These tumors begin in the breasts connective tissue, which is called the stroma.

What Are The Treatments For Breast Cancer

Treatments for breast cancer include

  • Surgery such as
  • A mastectomy, which removes the whole breast
  • A lumpectomy to remove the cancer and some normal tissue around it, but not the breast itself
  • Chemotherapy
  • Hormone therapy, which blocks cancer cells from getting the hormones they need to grow
  • Targeted therapy, which uses drugs or other substances that attack specific cancer cells with less harm to normal cells
  • Percent When The Cancer Is Caught In Its Earliest Stages

    Breast cancer is still the most prevalent cancer affecting women of all ethnicities in the United States. There have been astounding strides in breast cancer survival rates since BCAs founding 25 years ago. Today thanks to medical and scientific advances these are near 90 percent when the cancer is caught in its earliest stages.

    Despite the tremendous progress that has been made, our mission continues with a renewed sense of urgency. Especially on the heels of, and setbacks from, the COVID-19 pandemic, Wattenmaker points out. She says that BCA has set a stake in the ground, aiming for a 100 percent breast cancer survival rate by the close of this decade. It is an ambitious goal but one we believe can be achieved, she notes.

    As part of its outreach efforts, Wattenmaker says that BCA is increasing creative programming. With a strong focus on engagement and wellness. For example, it recently held its 2nd annual Get Fit For Hope challenge, which this year was expanded to include a wide swath of classes. It focused on exercise and well-being, most held virtually.

    Don’t Miss: Average Life Expectancy Stage 4 Breast Cancer

    Can Exercise Help Reduce My Risk Of Developing Breast Cancer

    Exercise is a big part of a healthy lifestyle. It can also be a useful way to reduce your risk of developing breast cancer in your postmenopausal years. Women often gain weight and body fat during menopause. People with higher amounts of body fat can be at a higher risk of breast cancer. However, by reducing your body fat through exercise, you may be able to lower your risk of developing breast cancer.

    The general recommendation for regular exercise is about 150 minutes each week. This would mean that you work out for about 30 minutes, five days each week. However, doubling the amount of weekly exercise to 300 minutes can greatly benefit postmenopausal women. The longer duration of exercise allows for you to burn more fat and improve your heart and lung function.

    The type of exercise you do can vary the main goal is get your heart rate up as you exercise. Its recommended that your heart rate is raised about 65 to 75% of your maximum heart rate during exercise. You can figure out your maximum heart rate by subtracting your current age from 220. If you are 65, for example, your maximum heart rate is 155.

    Aerobic exercise is a great way to improve your heart and lung function, as well as burn fat. Some aerobic exercises you can try include:

    • Walking.
    • Dancing.
    • Hiking.

    Remember, there are many benefits to working more exercise into your weekly routine. Some benefits of aerobic exercise can include:

    Signs Of Estrogen Dominance

    Tissue activation leads to breast cancer depending on ...

    Estrogen can be metabolized in your body in different ways. Some pathways lead to estrogen metabolites that can compromise your health. This can be a particular problem if your liver is not functioning well. Then your liver doesnt process estrogen metabolites and help remove them from your body, and you end up with more estrogen circulating, causing havoc and estrogen excess.

    ED can mean one of two things: you either have too much estradiol in relation to progesterone, or an imbalance in your estrogen metabolites .

    This can lead to the following symptoms:

    • Worsening PMS
    • Lumpy, painful or swollen breasts
    • Weight gain, particularly around the hips

    Read Also: What Is Stage 3a Breast Cancer

    What Is Niehs Doing

    NIEHS plays a leadership role in funding and conducting studies on the ways in which environmental exposures increase breast cancer risk. This research seeks to understand the role of environmental agents, such as toxic chemicals, in the initiation and progression of cancer, as well as genetic susceptibility. Identifying and reducing contact with environmental factors linked to breast cancer presents tremendous opportunity to prevent this disease.

    Sister Study The NIEHS Sister Study has recruited more than 50,000 sisters of women with breast cancer from the U.S. and Puerto Rico. This landmark observational study is looking at lifestyle and environmental exposures, as well as genetic and biological factors that may increase breast cancer risk. Important findings from this study follow.

    Two Sister Study An offshoot of the Sister Study, this study focuses on breast cancer in women younger than 50, who may have different breast cancer risk factors than older women. Approximately 1,300 women with young-onset breast cancer are participating, along with their sisters from the Sister Study and their biological parents. Some results from the study include the following.

    In-house NIEHS researchers have also studied how environmental exposures can interact with genetic factors to affect breast cancer risk.

    Some hallmark findings from BCERP follow.

    Who Is A Candidate For Brca Gene Testing

    This should be discussed with your health care provider or treatment team as this information is frequently updated. Guidelines for testing may include

    • a personal history of breast cancer diagnosis at a young age, bilateral breast cancer, breast and ovarian cancer diagnosis, or a personal history of ovarian cancer
    • family history of breast cancer at a young age or ovarian cancer and a personal history of breast cancer
    • family member with bilateral breast cancer, ovarian cancer, or both breast and ovarian cancer
    • relative with a known BRCA1 or BRCA2 mutation and
    • a male relative with breast cancer.

    You May Like: What Is Hr Positive Breast Cancer

    External Beam Radiation Therapy

    The following three sections refer to treatment using x-rays.

    Conventional external beam radiation therapy

  • a teletherapy “source” composed of
  • two nested stainless steel canisters welded to
  • two stainless steel lids surrounding
  • a protective internal shield and
  • a cylinder of radioactive source material, often but not always . The diameter of the “source” is 30 mm.
  • Historically conventional external beam radiation therapy was delivered via two-dimensional beams using kilovoltage therapy x-ray units, medical linear accelerators that generate high-energy x-rays, or with machines that were similar to a linear accelerator in appearance, but used a sealed radioactive source like the one shown above. 2DXRT mainly consists of a single beam of radiation delivered to the patient from several directions: often front or back, and both sides.

    Conventional refers to the way the treatment is planned or simulated on a specially calibrated diagnostic x-ray machine known as a simulator because it recreates the linear accelerator actions , and to the usually well-established arrangements of the radiation beams to achieve a desired plan. The aim of simulation is to accurately target or localize the volume which is to be treated. This technique is well established and is generally quick and reliable. The worry is that some high-dose treatments may be limited by the radiation toxicity capacity of healthy tissues which lie close to the target tumor volume.

    Intensity-modulated radiation therapy

    Do Antiperspirants Or Deodorants Cause Breast Cancer

    Breast cancer screening ‘leads to over-diagnosis’

    Research has shown that parabens can build up in breast tissues. However, this study did not show that parabens cause breast cancer or find a link between parabens and deodorant use.

    A 2002 study did not show any increased risk for breast cancer in women using an underarm deodorant or antiperspirant. A 2003 study showed an earlier age for breast cancer diagnosis in women who shaved their underarms more frequently and used underarm deodorants.

    We need more research to give us the answer about a relationship between breast cancer and underarm deodorants and blade shaving.

    You May Like: Can A Biopsy Tell Stage Of Cancer

    How Is Breast Cancer Diagnosed

    During your regular physical examination, your doctor will take a thorough personal and family medical history. He or she will also perform and/or order one or more of the following:

    • Breast examination: During the breast exam, the doctor will carefully feel the lump and the tissue around it. Breast cancer usually feels different than benign lumps.
    • Digital mammography: An X-ray test of the breast can give important information about a breast lump. This is an X-ray image of the breast and is digitally recorded into a computer rather than on a film. This is generally the standard of care .
    • Ultrasonography: This test uses sound waves to detect the character of a breast lump whether it is a fluid-filled cyst or a solid mass . This may be performed along with the mammogram.

    Based on the results of these tests, your doctor may or may not request a biopsy to get a sample of the breast mass cells or tissue. Biopsies are performed using surgery or needles.

    After the sample is removed, it is sent to a lab for testing. A pathologist a doctor who specializes in diagnosing abnormal tissue changes views the sample under a microscope and looks for abnormal cell shapes or growth patterns. When cancer is present, the pathologist can tell what kind of cancer it is and whether it has spread beyond the ducts or lobules .

    Effects On Pituitary System

    commonly develops after radiation therapy for sellar and parasellar neoplasms, extrasellar brain tumours, head and neck tumours, and following whole body irradiation for systemic malignancies. Radiation-induced hypopituitarism mainly affects and . In contrast, and deficiencies are the least common among people with radiation-induced hypopituitarism. Changes in -secretion is usually mild, and vasopressin deficiency appears to be very rare as a consequence of radiation.

    Read Also: Adjuvant Therapy For Breast Cancer

    Signs And Symptoms Of Breast Cancer

    In its early stages, breast cancer may not cause any symptoms. In many cases, a tumor may be too small to be felt, but an abnormality can still be seen on a mammogram.

    If a tumor can be felt, the first sign is usually a new lump in the breast that was not there before. However, not all lumps are cancer.

    Each type of breast cancer can cause a variety of symptoms. Many of these symptoms are similar, but some can be different. Symptoms for the most common breast cancers include:

    • a breast lump or tissue thickening that feels different than surrounding tissue and has developed recently
    • breast pain
    • changes to the appearance of the skin on your breasts
    • a lump or swelling under your arm

    If you have any of these symptoms, it doesnt necessarily mean you have breast cancer. For instance, pain in your breast or a breast lump can be caused by a benign cyst.

    Still, if you find a lump in your breast or have other symptoms, you should see your doctor for further examination and testing.

    What Are Breast Cancer Risk Factors How Do You Get Breast Cancer

    Risk factors that lead to the development of breast cancer ...

    Some of the breast cancer risk factors can be modified while others cannot be influenced . It is important to discuss these risks with a health care provider when starting new therapies .

    Several risk factors are inconclusive , while in other areas, the risk is being even more clearly defined .

    The following are risk factors for breast cancer:

    Also Check: What Is Stage 3 Cancer Mean

    Age At First Menstrual Period First Pregnancy And Menopause

    The earlier menstruation begins , the higher the risk of developing breast cancer.

    The later the first pregnancy occurs and the later menopause occurs, the higher the risk. Never having had a baby increases the risk of developing breast cancer. However, women who have their first pregnancy after age 30 are at higher risk than those who never have a baby.

    These factors probably increase risk because they involve longer exposure to estrogen, which stimulates the growth of certain cancers.

    Cytotoxics And Targeted Therapies

    are a relatively new class of cancer drugs that can overcome many of the issues seen with the use of cytotoxics. They are divided into two groups: small molecule and antibodies. The massive toxicity seen with the use of cytotoxics is due to the lack of cell specificity of the drugs. They will kill any rapidly dividing cell, tumor or normal. Targeted therapies are designed to affect cellular proteins or processes that are utilised by the cancer cells. This allows a high dose to cancer tissues with a relatively low dose to other tissues. Although the are often less severe than that seen of cytotoxic chemotherapeutics, life-threatening effects can occur. Initially, the targeted therapeutics were supposed to be solely selective for one protein. Now it is clear that there is often a range of protein targets that the drug can bind. An example target for targeted therapy is the BCR-ABL1 protein produced from the , a genetic lesion found commonly in and in some patients with . This has enzyme activity that can be inhibited by , a drug.

    Recommended Reading: Basal Type Breast Cancer

    Early Menstruation Or Late Menopause

    If you began having menstrual periods before age 12 or went through menopause after age 50, your risk of breast cancer is slightly higher than average. This may be because of the amount of the female hormone estrogen that your breasts have been exposed to throughout your lifetime. But the precise cause is not known.

    Second Cancers After Breast Cancer

    Dental Care Leads to Free Breast Cancer Screening

    Breast cancer survivors can be affected by a number of health problems, but often a major concern is facing cancer again. Cancer that comes back after treatment is called a recurrence. But some cancer survivors develop a new, unrelated cancer later. This is called a second cancer.

    Women whove had breast cancer can still get other cancers. Although most breast cancer survivors dont get cancer again, they are at higher risk for getting some types of cancer, including:

    • A second breast cancer
    • Salivary gland cancer
    • Melanoma of the skin
    • Acute myeloid leukemia

    The most common second cancer in breast cancer survivors is another breast cancer. The new cancer can occur in the opposite breast, or in the same breast for women who were treated with breast-conserving surgery .

    Read Also: De Novo Metastatic Breast Cancer Symptoms

    Is Birth Control Pills Bad For You Long

    There is some research that suggests taking the pill for a long time may increase your risk of developing certain types of cancer. However, the pill is generally safe to take over a long period of time. Birth control pills may increase your risk of breast cancer and cervical cancer over time, according to the American Cancer Society.

    Are There Any Other Questions I Should Ask My Doctor About Breast Cancer

    Yes. There are surely other questions you will wish to ask. Do not hesitate to be very open about your concerns with your doctor. There is constantly new information and new research available about breast cancer, whether BRCA-related new treatments or drugs or new treatment regiments and recommendations. The foregoing questions and comments should demonstrate that the diagnosis and treatment of breast cancer may not be a simple process. Even when all the information is available, there may be difficulties in deciding a proper course of action. However, this decision-making process has a better chance of success when you and the doctor are well informed and communicating effectively. Although the information here cannot be all-inclusive, we hope it will help you work through this process.

    Also Check: What Is Stage 3a Breast Cancer

    Your Race And Ethnicity

    White and Black women have the highest risk of developing breast cancer in their lifetime. Asian/Pacific Islander and Hispanic/Latina womens breast cancer rates fall in between two major groupings while American Indian and Alaska Native women are on the lowest end of risk.

    While white women are more likely to develop breast cancer than Black women overall, they tend to be diagnosed at an older age . Black women have the highest breast cancer rates among women under age 40. Black women make up a higher percentage of triple-negative breast cancer cases.

    What to do: If your race or ethnicity places you at higher risk, make sure you follow all screening recommendations to improve your chances of catching cancer early.

    What Are The Stages Of Breast Cancer

    Causes Of Breast Cancer

    There are two different staging systems for breast cancer. One is called anatomic staging while the other is prognostic staging. The anatomic staging is defined by the areas of the body where the breast cancer is found and helps to define appropriate treatment. The prognostic staging helps medical professionals communicate how likely a patient is to be cured of the cancer assuming that all appropriate treatment is given.

    The anatomic staging system is as follows:

    Stage 0 breast disease is when the disease is localized to the milk ducts .

    Stage I breast cancer is smaller than 2 cm across and hasn’t spread anywhere including no involvement in the lymph nodes.

    Stage II breast cancer is one of the following:

    • The tumor is less than 2 cm across but has spread to the underarm lymph nodes .
    • The tumor is between 2 and 5 cm .
    • The tumor is larger than 5 cm and has not spread to the lymph nodes under the arm .

    Stage III breast cancer is also called “locally advanced breast cancer.” The tumor is any size with cancerous lymph nodes that adhere to one another or to surrounding tissue . Stage IIIB breast cancer is a tumor of any size that has spread to the skin, chest wall, or internal mammary lymph nodes .

    Stage IV breast cancer is defined as a tumor, regardless of size, that has spread to areas away from the breast, such as bones, lungs, liver or brain.

    Also Check: How Do Doctors Treat Breast Cancer

    RELATED ARTICLES

    Popular Articles