Second Primary Tumors By Age At Diagnosis
We next analyzed risks for second primary breast cancers according to HR status and age at first cancer diagnosis . For women with a first HR-positive tumor, there was an inverse trend with age at diagnosis, with risk of any second primary cancer highest when cancer was first diagnosed before age 30 years , declining statistically significantly for age 3039 years and dropping to SIRs between 1.0 and 3.0 thereafter. This trend by age was observed irrespective of HR status of the second tumor.
What Are The Chances Of Dcis Recurrence
DCIS is non-invasive so women do not die of it. Their real concern arises if they develop invasive cancer and the cancer spreads. ” According to the study, the group of patients with the lowest risk has only a 2 percent chance of developing invasive cancer at 5 years and a 4 percent chance at 8 years.
One may also ask, can you get DCIS twice? DCIS is NOT invasive cancer. DCIS stays inside the breast milk duct. DCIS can be large or small, but it does NOT spread outside the milk duct into the surrounding normal breast tissue or into the lymph nodes or other organs. Yes, it does make it very unlikely that any type of breast cancer will be diagnosed again.
Likewise, people ask, what are the chances of DCIS recurrence after mastectomy?
The rate of locoregional recurrence was 4.2% in women younger than age 40 vs just 0.2% in women at least 50 years old, the study authors reported. The overall risk of having a locoregional recurrence after mastectomy for DCIS is very low, but it is higher in younger women.
Why does DCIS recur?
The researchers found 26 factors that could be linked to invasive breast cancer recurrence after DCIS. Positive margins: If the DCIS has positive margins, it means that some cancer cells were left behind at the cancer site and could eventually lead to a recurrence. Being premenopausal: Premenopausal women are younger.
How Quickly Do Breast Cancer Tumors Grow From Stage To Stage
Cancer cells divide and multiply quickly in such a way that as a tumor gets bigger, it divides and grows even faster. The average doubling time for breast cancer tumors is between 50 and 200 days. Breast cancer tumor growth rate is impacted by hormonal factors, such as hormone receptor status and HER2 status.
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How Will My Prognosis Affect My Treatment
Following surgery or radiation, your treatment team will determine the likelihood that the cancer will recur outside the breast. This team usually includes a medical oncologist, a specialist trained in using medicines to treat breast cancer. The medical oncologist, who works with your surgeon, may advise the use of tamoxifen or possibly chemotherapy. These treatments are used in addition to, but not in place of, local breast cancer treatment with surgery and/or radiation therapy.
What We Know About Getting Covid After The Vaccine
The NHS says you can still catch Covid-19, even if you are fully vaccinated.
And a PHE study has shown roughly one in five double-jabbed people could potentially still become infected with the Delta variant.
The good news is that the majority of these infections are likely to be mild or asymptomatic.
People start gaining some protection against the virus after around three weeks after the first jab, and are best protected two weeks after the second.
Sir Peter Horby, chair of the New and Emerging Respiratory Virus Threats Advisory Group , told the BBCs Andrew Marr: What we know with the vaccines is that they are remarkably effective at preventing hospitalisations and death. They are less effective at preventing infection.
Its really important for people to realise that as we increase the vaccination rates, and most older people are vaccinated, we will see breakthrough infections.
That does not mean that the vaccinations dont work breakthroughs are expected. What we want to do is prevent hospitalisations and deaths, and the vaccines do that very effectively.
The World Health Organisation has said: The Covid-19 vaccines produce protection against the disease, as a result of developing an immune response to the SARS-Cov-2 virus.
Developing immunity through vaccination means there is a reduced risk of developing the illness and its consequences.
This immunity helps you fight the virus if exposed.
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What Causes Breast Cancer Recurrence
The goal of cancer treatments is to kill cancer cells. But, cancer cells are tricky. Treatments can reduce tumors so much that tests dont detect their presence. These weakened cells can remain in the body after treatment. Over time, the cells get stronger. They start to grow and multiply again.
Even surgery to remove a cancerous tumor isnt always 100% effective. Cancer cells can move into nearby tissue, lymph nodes or the bloodstream before surgery takes place.
After Surviving Breast Cancer What Are My Chances Of Getting Cancer In The Other Breast
There are a number of a large studies with ten-year follow up or more that have estimated that the risk of getting cancer in the other breast increases 0.2 to 0.4% per year. Therefore if a cancer survivor lives another 20 years after her diagnosis, her risk of developing a breast cancer on the opposite side ranges from 4 to 8%. The risk is lower if she has chemotherapy or hormone therapy as part of her original treatment , which translates to a 2 to 4% 20-year risk. These figures represent the average risk of developing contralateral breast cancer in the future. Some women are at higher risk based on their age or the characteristics of their tumor.
Those at higher risk include:
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How Is Breast Cancer Recurrence Managed Or Treated
Your treatment depends on the type of cancer recurrence, as well as past treatments. If cancer develops in a reconstructed breast, your surgeon may want to remove the breast implant or skin flap.
Treatments for local and regional breast cancer recurrence may include:
- Mastectomy: Your surgeon removes the affected breast and sometimes lymph nodes.
- Chemotherapy:Chemotherapy circulates in blood, killing cancer cells.
- Hormone therapy:Tamoxifen and other hormone therapies treat cancers that thrive on estrogen .
- Immunotherapy:Immunotherapy engages your bodys immune system to fight cancer.
- Radiation therapy: High-energy X-ray beams damage and destroy cancer cells.
- Targeted therapy: Treatments target specific cancer cell genes or proteins.
Why People Are Getting Covid
Were seeing more reinfections now than during the first year of the pandemic, which is not necessarily surprising, Dr. Esper says.
The CDC says cases of COVID-19 reinfection;remain rare but possible. And with statistics and recommendations changing so quickly and so frequently, that rare status could always change, as well.
Dr. Esper breaks down the reasons behind reinfection.
Health Disparities In Young African Americans
In addition to these unique issues, research has shown that young African American women face even greater challenges.
- African American women under age 35 have rates of breast cancer two times higher than caucasian women under age 35.14
- African Americans under age 35 die from breast cancer three times as often as caucasian women of the same age.14
- Researchers believe that access to healthcare and the quality of healthcare available may explain these disparities. But scientists continue to investigate.
- Research also shows that young African Americans are more likely to get aggressive forms of breast cancer than anyone else.14
Screening: A Preventive Measure For Cancer
Cancer detected at an early stage gives the best chance of survival. But when management is delayed, patients are more likely to face greater problems and higher costs of care.
If cancer is in your genes, or if you have a risk for certain type of malignancy, its best to do regular screening, advises Dr. Ladera. Screening and detecting cancer at the earliest stage offers your best chance for cure.
Compared to early diagnosis, screening is a totally different strategy that checks on illnesses that might be present, even if one is presumed healthy.
There are three Rs that need to be assed when doing cancer screening: risk factors, recommendations and rationale.
By constantly being in check of ones health, the effects of cancer on personal and economical aspects can be reduced, notes Dr. Jorge Ignacio, Cancer Institute director of the UP-PGH.
Unfortunately, many patients overlook the cancer screening process due to multiple factors.
Some are worried that they might test positive for cancer, others fear the procedure itself, some are unaware of where to go and how to book a screening schedule, and to a huge chunk of patients, they view screenings and checkups as another financial burden for their families.
The PGH Cancer Institute shared that pre-pandemic, the hospital would cater to an average of 120 patients daily. But in 2020 onwards, an average of 20 percent of cancer patients have not returned for their regular treatments, and some have already relapsed.
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Minimize The Risk Of Second Cancers
Keep Track of Your Health Care
- Keep a health journal.
- Write down everything you want to ask your health care team. Take notes and keep track of questions between visits.
- Make a list of your medications. Bring this information to the visit along with all of your medication bottles. This will help the health care team keep track of all the medications you are taking, including vitamins and over-the-counter medications.
- Take notes during health care appointments.
- Keep all of your health records together and bring this information with you to health care appointments.
- Bring extra copies of important documents to give to appropriate health care team members. You can also fax or mail these before your appointment. Having the health care team read your documents may be an easier way for you to communicate.
- Store pamphlets, information about medication side effects and important phone numbers in your notebook so that everything is in one place.
One of the most important things you can do is to follow-up with a health care team that is well-informed about survivorship care. Good medical care and screening can help detect second cancers early.
- Try to find balance with a healthy lifestyle.
- Know if your family has a history of cancer.
- Use a health journal to prepare for your next visit with a member of your health care team.
Can Second Cancers Be Prevented
Not always. You cannot control some risk factors, such as having a specific cancer treatment in the past. But you can do some things to reduce your general cancer risk, such as:
Exercising regularly and eating a healthy diet
Limiting alcohol use
You can talk with a genetic counselor about getting tested for gene mutations that are linked to cancer. If tests show that you have the mutation, you might choose a treatment to lower your risk of future cancers.
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More Than One Primary Cancer
Several members of my family have had two different primary cancers; my sister has had three primaries, all early stage and treated only with surgery (renal cell carcinoma dx 1995, papillary thyroid cancer, dx 2004 and non-small cell lung cancer, dx 2004. She is now cancer free and has never had a relapse of any of her cancers. However, this year, when her doctor scheduled annual follow-up CT scans, her insurance company refused to pay for them. We have genetic cancers in our family, and are in the process of appealing.
I have read that 10% of cancer survivors have a second primary, and 0.01% of allsurvivors have three primaries.
Early Detection Saves Lives
Melissa is one of the resource persons in the second episode of Tita Hope Talks: Tackling Access to Cancer Diagnosis and Navigation in the COVID-19 Era, a timely discussion on the importance of early diagnosis in cancer care with or without the pandemic.
An initiative by Hope from Within, a multi-stakeholder cancer advocacy campaign spearheaded by MSD in the Philippines, Tita Hope Talks seeks to remind the public to consult their doctor as soon as they spot something unusual and not to put off preliminary screening.
Hosted by broadcast journalist and health advocate Niña Corpus, Tita Hope Talks gathers experts and health stakeholders to discuss their perspective and provides their insights on various issues surrounding cancer care.
The sessions panel speakers included Dr. Beverly Ho, Disease Prevention and Control Bureau director of the Department of Health; Dr. Jorge Ignacio, Cancer Institute director of the UP-PGH; Dr. Guia Ladrera, Oncology Department section head of the Lung Center of the Philippines; Melissa Ongsue-Lee,VP for sales and marketing of Hi-Precision Diagnostics; Amiel Herrera, founder/CEO of Medcheck; and Melissa de Leon, president of breast cancer support group Project Pink.
The role of cancer screening in early detection and its impact on survival is well documented in breast, cervical, lung and colorectal cancers.
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Do I Need Cancer Screenings More Often Than Other People
You are probably having screenings to check for a recurrence of the first cancer. Your doctor can also tell you if you need to be screened for other cancers. You should get these on the schedule your doctor recommends. If you have a high risk of cancer, you might have screenings more often than other people. Tell your doctor as much as possible about your family history and past cancer treatment.
What Is The Average American Womans Risk Of Being Diagnosed With Breast Cancer At Different Ages
Many women are more interested in the risk of being diagnosed with breast cancer at specific ages or over specific time periods than in the risk of being diagnosed at some point during their lifetime. Estimates by decade of life are also less affected by changes in incidence and mortality rates than longer-term estimates. The SEER report estimates the risk of developing breast cancer in 10-year age intervals . According to the current report, the risk that a woman will be diagnosed with breast cancer during the next 10 years, starting at the following ages, is as follows:;
- Age 30 . . . . . . ;0.49%
- Age 40 . . . . . . ;1.55%
- Age 50 . . . . . . ;2.40%
- Age 60 . . . . . . ;3.54%
- Age 70 . . . . . . ;4.09%
These risks are averages for the whole population. An individual womans breast cancer risk may be higher or lower depending on known factors, as well as on factors that are not yet fully understood. To calculate an individual womans estimated breast cancer risk, health professionals can use the Breast Cancer Risk Assessment Tool, which takes into account several known breast cancer risk factors.;
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Using Your Family History
You should certainly share your family history with your medical team. Your doctors might advise genetic counseling or genetic testing if your family history suggests that you could be carrying a breast cancer gene.
Some red flags include:
- Cancer of;any;kind before the age of 50
- More than one relative with the same type of cancer
- One family member who has more than one type of cancer
- A family member who has cancer not typical for that gender, such as breast cancer in a male
- Certain combinations of cancer, such as the combination of breast cancer with ovarian cancer, uterine cancer, colon cancer, prostate cancer, pancreatic cancer, or melanoma
- Cancer in both of one organ, for example, bilateral breast or ovarian cancer
Symptoms Of Salivary Gland
No problem asking any questions it helps- Well about 2 years ago a lymoh node under my chin seemed to pop in and out but it seemed to be everytime I had a sinus infection so ignored it and chalked it up to sinsus issues
then last October it stayed out and seemed a little larger – so while at the dentist he said due to my background and prior radiation I should see a oral surgeon in his office ..who sent me to his ENT
so no real symptoms except for the enlarged lymph node – guess for us – enlarged lymph nodes are not good mist of the time
Take care Cathy
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