Symptoms Of Lobular Breast Cancer
Lobular breast cancer sometimes begins without symptoms. It may show as an abnormal area on a mammogram, which leads to further examination.
Spotting ILC on a mammogram can be difficult because the cancer cells spread in a line rather than in a distinctive lump, as in IDC. Magnetic resonance imaging imaging is reported to provide more sensitive images that may show the cancer better.
The first symptom of ILC is sometimes a thickening or hardening of a portion of the breast. This thickening can be felt by touch, but it feels different from the classic lump associated with IDC, the more common breast cancer.
Other symptoms of ILC may include:
- swelling or fullness in a part of the breast, or in the whole breast
- a change in the skin texture in a part of the breast
- dimpling in the breast
The exact cause of ILC is currently unknown. But there are some risk factors that are associated with ILC. These can include:
- taking hormone replacements, for menopause for example
Although people can be diagnosed with lobular breast cancer at any age, its most common in women ages 55 years and older. Research suggests that hormone replacement therapy after menopause, especially with progesterone, may increase the risk of this type of cancer.
Am I Still At Risk Of Local Recurrence If I Have Had A Mastectomy
Yes. Local recurrence can also happen after a mastectomy, although the likelihood is usually low.
Some of the signs of local recurrence after mastectomy include
- A lump or raised bump in or under the skin, especially near the previous mastectomy scar
- Changes to the skin, including redness or thickening
After reconstruction a local recurrence can appear at the suture line of the flap or in front of the implant. When its in the skin itself, it is red and raised. Reconstruction rarely if ever hides a recurrence. With implants, the recurrences are in front of the implant. With a flap, the recurrences are not in the flap itself but along the edge of the breast skin.
Local recurrence after mastectomy is often described as a chest wall recurrence, which isnt entirely accurate because it implies that the cancer is in the muscle or bone. But usually such a recurrence appears in the skin and fat where the breast was before, and only rarely does it include the muscle.
Ninety percent of local recurrences following mastectomy happen within the first five years after the mastectomy. Approximately 20 to 30 percent of women with local recurrences after mastectomy have already been diagnosed with metastatic disease, and another 20 to 30 percent will develop it within a few months of diagnosis. Therefore, just as with local recurrences after breast conservation, tests should be done to look for distant disease.
What Tumor Factors Threaten My Life More
There are important tumor biology factors not well reflected in survival statistics by breast cancer stage. Below we list a few important factors that carry a higher risk to life beyond just the stage of cancer. You must ask your surgeon or medical oncologist to explain your receptor status and give you a copy of your biopsy pathology report.
Triple Negative Receptor breast cancer
Triple negative breast cancer is considered a more aggressive breast cancer. Invariably it does require chemotherapy. If you have triple negative breast cancer the risk of dying is higher than the standard statistics usually quoted for a particular stage of breast cancer . Learn more about Triple Negative Breast Cancer with our video lesson
HER2-Positive breast cancer
HER2-positive breast cancers are also more aggressive tumors. But the good news is that we now have incredibly effective, targeted chemotherapy and immunotherapy for HER2-positive cancers. Our video lesson covers HER2-Positive Breast Cancer in more detail .
Breast Cancer at a Young Age
Women younger than 40 have a higher chance of being diagnosed with a more advanced stage breast cancer. Also, the specific cancer type younger women develop has a higher chance of being more aggressive . As a result, age is a relative risk factor for survival.
Untreated breast cancer
Teaching everyone to be an expert in their own breast cancer care.
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Will I Die Of Breast Cancer
This is a difficult question to answer early in your cancer care but it is still worth asking. Many people just diagnosed with cancer have no idea how much of a risk to their life their unique situation poses. Most breast cancers carry a low risk of recurrence, especially early-stage cancers. The answer is usually reassuring.
Invasive Ductal Carcinoma Stages
Invasive ductal carcinoma stages provide physicians with a uniform way to describe how far a patients cancer may have spread beyond its original location in a milk duct. This information can be helpful when evaluating treatment options, but it is not a prognostic indicator in and of itself. Many factors can influence a patients outcome, so the best source of information for understanding a breast cancer prognosis is always a physician who is familiar with the patients case.
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M Categories For Breast Cancer
M followed by a 0 or 1 indicates whether the cancer has spread to distant organs — for example, the lungs, liver, or bones.
M0: No distant spread is found on x-rays or by physical exam.
cM0: Small numbers of cancer cells are found in blood or bone marrow , or tiny areas of cancer spread are found in lymph nodes away from the underarm, collarbone, or internal mammary areas.
M1: Cancer has spread to distant organs as seen on imaging tests or by physical exam, and/or a biopsy of one of these areas proves cancer has spread and is larger than 0.2mm.
Breast Cancer Survival Rates By Stage And Age
The relative 5-year survival rate for breast cancer is 91%. This means that those who have breast cancer are, on average, 91% as likely as those who dont have the disease to live for at least 5 years after their diagnosis. The survival rate is an estimate across the population, and an individuals chance of survival is dependent on their specific characteristics and the nature of the tumour, such as the stage of the breast cancer at diagnosis, the age, gender and the subtype of the breast cancer .
The 5-year survival rate for Stage 1 breast cancer is, on average, 100% and Stage 2 is 95%. For locally advanced cancers the survival rate is 81%, while the 5-year survival rate for Stage 4 is significantly lower at 32%.
The 5-year survival rate also differs depending on the age group. For those aged over 85, the 5-year survival rate is 75%, while for those between 40 and 44 years of age it is 93%.
While the 5-year survival rate post-diagnosis is 91%, the survival rate 10 years after diagnosis of breast cancer is 86%.
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What Are The Signs Of Breast Cancer Recurrence
If you have a local recurrence or new primary breast cancer, you may find symptoms similar to an initial breast cancer. This includes:
- A new lump in the breast, armpit area or around the collarbone
- A change in breast size or shape
- Changes to the nipple, such as sores or crusting, an ulcer or inverted nipple
- Clear or bloody nipple discharge
- Changes to the skin including redness, puckering or dimpling
- Breast tenderness or pain
If your breast cancer has spread to other parts to the body, known as distant recurrence, there are a number of possible symptoms, including:
- Unexpected weight loss or change in appetite
- Severe or ongoing headaches
However, symptoms will vary depending on where the secondary cancer presents, and some primary and secondary cancers may not present any obvious symptoms. Sometimes recurrence is identified on a scan or blood test that was done for a reason other than breast cancer.
If you have any health concerns or symptoms that are new or persistent, speak with you GP or treating physician.
How Can I Prevent Breast Cancer Recurrence
There is no definitive way to prevent breast cancer or breast cancer recurrence. However, treatments such as surgery, chemotherapy, radiotherapy, targeted therapy and/or hormone therapy do reduce the risk of recurrence, depending on the type and stage of the cancer. These can be discussed with your treatment team.
Understanding breast cancer risk factors and participating in regular breast screening through BreastScreen in Australia and BreastScreen Aotearoa in New Zealand can help to pick up any breast changes. Discussion with your healthcare team can help to catch any changes or abnormalities early and act on them.
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Whats The Outlook For Metastatic Breast Cancer
The right treatment plan can improve survival for people with metastatic breast cancer. However, survival rates vary and are dependent on a number of factors including type/biology of the breast cancer, parts of the body involved and individual characteristics. About 1 in 3 women live at least five years after diagnosis. Some live 10 years or longer. Your care team will discuss your prognosis with you in more detail.
Relative Survival Rate By Stage
The survival rates by stage are based on the stage at the time of diagnosis. Youâve probably been given a number and letter for your cancer stage. Here, the terms localized, regional, and distant are used instead of numbers and letters. Hereâs what they mean and the 5-year relative survival rates for each:
- Localized breast cancer is only in the breast. This includes stage IA , some IIA , and some IIB . The 5-year relative survival rate is 99%.
- Regional breast cancer has spread to nearby tissue or lymph nodes. This includes stage IB , some IIA , some IIB , and all stage III . The 5-year relative survival rate is 86%.
- Distant breast cancer has spread to other parts of the body. This includes stage IV, pronounced âstage 4â). The 5-year relative survival rate is 28%.
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What To Know In The Long
Stage 1A breast cancer is a generally favorable and treatable diagnosis, the experts said. But it does still involve long-term care and consideration.
Depending on the type of breast cancer, patients may need to take medication endocrine therapy, also called anti-hormone therapy for five to 10 years. For most stage 1 patients, though, itâs just five years, Mouabbi said.
People whoâve had stage 1 breast cancer also need to stay on top of screening in the future, the experts said.
âThe highest risk factor for another breast cancer is a prior history of breast cancer,â Mouabbi said. Thatâs why itâs so important that, once a cancer patient is in remission, they continue regular breast cancer screening, including mammograms and physical exams.
âThe most important thing is catching cancer in this early stage,â Ziedman agreed, adding that some people with a family history or genetic risks for cancer may need to start regular screenings much earlier.
Is Stage 1 Breast Cancer A Big Deal
Stage 1. Stage 1 breast cancer means the tumor is very small and either has not spread or may have a tiny bit of spread in a nearby lymph node. A cancer that has spread into the surrounding area is referred to as invasive breast cancer. Stage 1A: The tumor is very small and has not spread to the lymph nodes.
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Survival Of Breast Cancer Based On Stage
Statistics are given below for the overall survival rates for breast cancer based on certain stages of disease development.
I made this page many years ago, when there was nothing like this data available on the internet. Recently this page has been up-dated with the most recent statistics that we can find. Prognosis will be even better than the numbers here suggest because modern targeted treatments have improved a lot.
Breast cancer staging is determined by many factors and these include:-
- The presence and size of a tumor
- Whether the tumor is node negative or positive, this means whether lymph nodes are involved or not
- If the cancer has metastasized beyond the breast
If breast cancer is diagnosed and it is determined that there is no metastasis to the lymph nodes then the chances of survival are extremely good.
Once breast cancer has spread to the lymph nodes the mode of treatment tends to shift to the chemotherapy medicines, and the odds of survival are somewhat lower.
Can Stage 1 Breast Cancer Metastasize
When cancer spreads beyond the area where it originally developed, its called metastatic breast cancer. Breast cancers found in early stages, especially DCIS, are less likely to metastasize or come back after treatment, but its not possible to say for sure.
Breast cancers caught early have a very positive prognosis. According to the National Cancer Institute Surveillance, Epidemiology, and End Results Program, 99 percent of patients with cancers diagnosed when still confined to the breast are alive five years later.
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Navratilova Diagnosed With Stage 1 Throat And Breast Cancer
Tennis legend Martina Navratilova said Monday she has been diagnosed with both Stage 1 throat cancer and breast cancer.
Tennis legend Martina Navratilova said Monday she has been diagnosed with both throat cancer and breast cancer.
This double whammy is serious but still fixable, said the 66-year-old in a statement. Im hoping for a favorable outcome. Its going to stink for a while, but Ill fight with all have I got.
Navratilovas fighting spirit is well-documented she won a total of 59 Grand Slam titles — in singles, doubles and mixed doubles. And shes already beaten cancer once before.
After discovering an enlarged lymph node in her neck during the WTA Finals in Fort Worth back in November, she underwent testing. That was when doctors discovered Stage 1 throat cancer and later Stage 1 breast cancer. Specifically, it is human papillomavirus , one of the more treatable cancers.
Thinking of @Martina today and supporting her journey, like she did mine, with love and prayers. This is a woman who takes on challenges with strength and resilienceYou got this, Martina!
Navratilova wont be working the upcoming Australian Open for Tennis Channel, but hopes to arrange some Zoom appearances in the near future.
Navratilova told her good friend Pam Shriver several weeks ago, ahead of the public announcement.
Shriver, an analyst for Tennis Channel and ESPN, won 79 doubles titles playing with Navratilova, including 21 majors.
Histopathological Classification Of Breast Cancer
Table 1 describes the histologic classification of breast cancer based on tumor location. Infiltrating or invasive ductal cancer is the most common breast cancerhistologic type and comprises 70% to 80% of all cases.
|Paget disease with intraductal carcinoma|
|Paget disease with invasive ductal carcinoma|
- Primary lymphoma.
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What Should A Person With Stage 0 Or Stage 1 Breast Cancer Expect Regarding Treatment
Even though Stage 0 breast cancer is considered non-invasive, it does require treatment, typically surgery or radiation, or a combination of the two. Chemotherapy is usually not part of the treatment regimen for earlier stages of cancer.
Stage 1 is highly treatable, however, it does require treatment, typically surgery and often radiation, or a combination of the two. Additionally, you may consider hormone therapy, depending on the type of cancer cells found and your additional risk factors. Like stage 0, Chemotherapy is often not necessary for earlier stages of cancer.
Material on this page courtesy of National Cancer Institute
Medically Reviewed on April 15, 2020
Influence Of Dfti And Other Related Factors On Mortality Risk
A Cox proportional hazards model was used to examine the relationship of patient survival with the relevant variables . The DFTI, hospital level, and hospital ownership were nonsignificant predictors of mortality. ER, PR, and HER2 status were protective factors for mortality risk after other related factors were controlled for. Tumor size, number of involved lymph nodes, and cancer stage also were positively correlated with mortality risk .
Table 2 Influence of DFTIs and other related factors on mortality risk in patients with confirmed breast cancer.
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Stage 1 Breast Cancer: Treatment And Prognosis
- A stage 1 breast cancer diagnosis usually means there is a small tumor in the breast, perhaps with a low amount of lymph node involvement but no further spread.
- Stage 1 breast cancer treatment could include some combination of surgery, lymph node dissection, chemotherapy, hormonal therapy, targeted therapy, and immunotherapy.
- The prognosis for stage 1 breast cancer is very good, with a five-year-survival rate of 99 percent.
Breast cancer is classified into different stages based on the tumors size and whether cancer cells have spread to other parts of the body. Determining your cancers stage through a mammogram and other imaging techniques can help your doctor determine your prognosis and the best treatment options.
Oncologists classify breast cancer from stage 1 to stage 4 . Cancer specialists determine this classification by using the TNM system, which stages tumors based on:
- Tumor size How large is the primary tumor?
- Node Are there cancer cells in lymph nodes?
- Metastasis Has the cancer metastasized to other parts of the body?
Each letter is assigned a number, often with a letter following it. A lower number corresponds to early-stage, localized breast cancer, and a higher number indicates more advanced, metastatic breast cancer.
Other information is also used to better understand the stage of the cancer. These details may include:
Following a breast cancer diagnosis, a doctor will determine the most effective treatment based on the cancers stage.