What Is Metastatic Breast Cancer
Breast cancer usually begins in the ducts that carry milk to the nipple, and can metastasize reach other parts of the body when the cancer cells get into the blood or lymph systems. Most of the time, cancer cells die at some point in the process of trying to spread. But, if conditions are favorable for the cancer cells, some of them are able to form new tumors in other parts of the body. Metastatic cancer cells can also remain inactive at a distant site for many years before they begin to grow again, if at all.
What Is Cancer Staging
Staging is a way of describing how extensive the breast cancer is, including the size of the tumor, whether it has spread to lymph nodes, whether it has spread to distant parts of the body, and what its biomarkers are.
Staging can be done either before or after a patient undergoes surgery. Staging done before surgery is called the clinical stage, and staging done after surgery is called the pathologic stage. Doctors use diagnostic tests to find out the cancer’s stage, so staging may not be complete until all of the tests are finished. Knowing the stage helps the doctor recommend the best kind of treatment and can help predict a patient’s prognosis, which is the chance of recovery. There are different stage descriptions for different types of cancer.
This page provides detailed information about the system used to find the stage of breast cancer and the stage groups for breast cancer, such as stage IIA or stage IV.
How Is Breast Cancer Treated
There are several breast cancer treatment options, including surgery, chemotherapy, radiation therapy, hormone therapy, immunotherapy and targeted drug therapy. Whats right for you depends on many factors, including the location and size of the tumor, the results of your lab tests and whether the cancer has spread to other parts of your body. Your healthcare provider will tailor your treatment plan according to your unique needs. Its not uncommon to receive a combination of different treatments, too.
Breast cancer surgery
Breast cancer surgery involves removing the cancerous portion of your breast and an area of normal tissue surrounding the tumor. There are different types of surgery depending on your situation, including:
Chemotherapy for breast cancer
Your healthcare provider may recommend chemotherapy for breast cancer before a lumpectomy in an effort to shrink the tumor. Sometimes, its given after surgery to kill any remaining cancer cells and reduce the risk of recurrence . If the cancer has spread beyond your breast to other parts of your body, then your healthcare provider may recommend chemotherapy as a primary treatment.
Radiation therapy for breast cancer
Radiation therapy for breast cancer is typically given after a lumpectomy or mastectomy to kill remaining cancer cells. It can also be used to treat individual metastatic tumors that are causing pain or other problems.
Hormone therapy for breast cancer
Immunotherapy for breast cancer
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Peeling Scaling Or Flaking Skin
Dont immediately be alarmed if you notice peeling, scaling, or flaking on your breasts or the skin around your nipples. This is a symptom of breast cancer, but it can also be a symptom of atopic dermatitis, eczema, or another skin condition.
After an exam, your doctor may run tests to rule out Pagets disease, which is a type of breast cancer affecting the nipples. It can also cause these symptoms.
When To Seek Medical Advice
You should see a doctor as soon as you notice or suspect any changes in your breasts.
Nonetheless, remember that self-exams dont replace mammograms and other screening tests.
Having screening tests by a health specialist can help detect breast cancer even before any symptoms appear, which gives you a better chance of successful treatment.
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Inflammatory Breast Cancer Symptoms
Unlike other breast cancers, inflammatory breast cancer rarely causes breast lumps and may not appear on a mammogram. Inflammatory breast cancer symptoms include:
- Red, swollen, itchy breast that is tender to the touch
- The surface of the breast may take on a ridged or pitted appearance, similar to an orange peel
- Heaviness, burning, or aching in one breast
- One breast is visibly larger than the other
- Inverted nipple
- No mass is felt with a breast self-exam
- Swollen lymph nodes under the arm and/or above the collarbone
- Symptoms unresolved after a course of antibiotics
Unlike other breast cancers, inflammatory breast cancer usually does not cause a distinct lump in the breast. Therefore, a breast self-exam, clinical breast exam, or even a mammogram may not detect inflammatory breast cancer. Ultrasounds may also miss inflammatory breast cancer. However, the changes to the surface of the breast caused by inflammatory breast cancer can be seen with the naked eye.
Symptoms of inflammatory breast cancer can develop rapidly, and the disease can progress quickly. Any sudden changes in the texture or appearance of the breast should be reported to your doctor immediately.
For women who are pregnant or breast-feeding, redness, swelling, itchiness and soreness are often signs of a breast infection such as mastitis, which is treatable with antibiotics. If you are not pregnant or nursing and you develop these symptoms, your doctor should test for inflammatory breast cancer.
Risk Factors For Breast Cancer
There are several risk factors that increase your chances of getting breast cancer. However, having any of these doesnt mean you will definitely develop the disease.
Some risk factors cant be avoided, such as family history. You can change other risk factors, such as smoking. Risk factors for breast cancer include:
- Age. Your risk of developing breast cancer increases as you age. Most invasive breast cancers are found in women over 55 years old.
- Drinking alcohol. Alcohol use disorder raises your risk.
- Having dense breast tissue. Dense breast tissue makes mammograms hard to read. It also increases your risk of breast cancer.
- Gender. According to the
While there are risk factors you cant control, following a healthy lifestyle, getting regular screenings, and taking any preventive measures your doctor recommends can help lower your risk of developing breast cancer.
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Early Signs And Symptoms Of Breast Cancer
Chances are, you or someone you know has been affected by breast cancerin 2018, there was an estimated 3.6 million American women living with a diagnosis of breast cancerCancer Stat Facts: Female Breast Cancer. National Cancer Institute. Accessed 10/11/2021. . And by the end of 2021, an estimated 281,550 more women will join that group, making breast cancer the second most common female cancer after skin cancer. While breast cancer deaths have fallen over the years as more effective screening and treatments have evolved, breast cancer will still claim an estimated 43,600 womens lives in 2021.
The key to survival, statistics show, is early diagnosis and treatment, before the cancer has spread beyond the breast. Its important to keep a watchful eye on your breast health and be aware of changes that could be early signs of breast cancer.
Heres what to watch for.
Advanced Cancer That Progresses During Treatment
Treatment for advanced breast cancer can often shrink the cancer or slow its growth , but after a time, it tends to stop working. Further treatment options at this point depend on several factors, including previous treatments, where the cancer is located, a woman’s menopause status, general health, desire to continue getting treatment, and whether the hormone receptor status and HER2 status have changed on the cancer cells.
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Breast Cancer Signs And Symptoms
Knowing how your breasts normally look and feel is an important part of your breast health. Although having regular screening tests for breast cancer is important, mammograms do not find every breast cancer. This means it’s also important for you to know what your breasts normally look and feel like, so youll be aware of any changes in your breasts.
The most common symptom of breast cancer is a new lump or mass . A painless, hard mass that has irregular edges is more likely to be cancer, but breast cancers can be also soft, round, tender, or even painful.
Other possible symptoms of breast cancer include:
- Swelling of all or part of a breast
- Skin dimpling
- Breast or nipple pain
- Nipple or breast skin that is red, dry, flaking, or thickened
- Nipple discharge
- Swollen lymph nodes under the arm or near the collar bone
Many of these symptoms can also be caused by benign breast conditions. Still, its important to have any new breast mass, lump, or other change checked by an experienced health care professional so the cause can be found and treated, if needed.
Remember that knowing what to look for does not take the place of having regular screening for breast cancer.Screening mammography can often help find breast cancer early, before any symptoms appear. Finding breast cancer early gives you a better chance of successful treatment.
Advanced Breast Cancer Signs
The advanced stage of breast cancer can be scary because of the aggressive spread to other body parts.
Yet still, you need to discuss the symptoms with a doctor who can recommend the best treatment options to kill cancer cells that are damaging multiple organs. That can include radiation treatments and chemotherapy.
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What Do Lumps In My Breast Mean
Many conditions can cause lumps in the breast, including cancer. But most breast lumps are caused by other medical conditions. The two most common causes of breast lumps are fibrocystic breast condition and cysts. Fibrocystic condition causes noncancerous changes in the breast that can make them lumpy, tender, and sore. Cysts are small fluid-filled sacs that can develop in the breast.
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Does Stage 1 Breast Cancer Require Chemotherapy
In addition to surgery and radiation therapy, stage 1 breast cancer treatment may require chemotherapy, powerful drugs that attack all fast-growing cells in the body. In the past, almost all patients had chemotherapy. Today, the doctor may perform gene tests to help determine whether chemotherapy is likely to benefit you, or if its not necessary because your cancer isnt likely to recur after surgery and other treatment.
Chemotherapy may or may not be used along with other drugs such as hormone therapy, targeted therapy and/or immunotherapy. Your care team will determine which options may be most appropriate by examining your cancers specific characteristics. Patients typically take these drugs after surgery to kill the primary cancer.
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Checking The Lymph Nodes
The usual treatment is surgery to remove the cancer. Before your surgery you have an ultrasound scan to check the lymph nodes in the armpit close to the breast. This is to see if they contain cancer cells. If breast cancer spreads, it usually first spreads to the lymph nodes close to the breast.
Depending on the results of your scan you might have:
- a sentinel lymph node biopsy during your breast cancer operation
- surgery to remove your lymph nodes
You may have other treatments after surgery.
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When Should I See My Doctor
See your doctor or healthcare professional if you notice symptoms of possible breast cancer, such as a lump, pain, itch, nipple discharge or dimpling, or if you have any concerns about your breast cancer risk.
Your doctor or healthcare professional will assess you and work out if you need further tests. If required, they can refer you to a local service and provide necessary follow-up care.
What Are The Symptoms Of Stage 1 Breast Cancer
Common symptoms include swollen breast tissue, a new lump in the breast, a sore chest, and rib cage discomfort.
What are the symptoms of stage 1 breast cancer?
Common symptoms include swollen breast tissue, a new lump in the breast, a sore chest, and rib cage discomfort. A new lump in the skin of the breast is not necessarily cancer either. There are other benign tumors that can form on or within a mammary gland such as an abscess or fat necrosis. The formation of a secondary tumor of another type must also be considered leading to an enlarged node. Breast cancer may present with painless lymph nodes near armpit areas, slippage from its normal position, pea sized masses that don’t move when pressed upon but instead remain still and sometimes dark lumps or bumps under nipple area ducts which upon removal yield blood if biopsied .
One of the most common symptoms is pain. Other possible symptoms are changes in size, discharge from the nipple, and redness or swelling in the part of the breast or underneath it. While there can be other causes for these symptoms other than cancer, it should always be checked by a physician. Other signs that might indicate stage 1 breast cancer are new lumps found inside the breasts and masses found outside on top of the skin.
- Dimpling skin over the breast
- Change in size, shape or texture of breast tissue
- Breast pain
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Who Provides Breast Cancer Treatment
A medical team may involve several different health professionals. It may include a GP, a radiologist, an oncologist, a breast care nurse, a surgeon and other allied health professionals such as counsellors and therapists. Having a multi-disciplinary team means a patient can receive the best care possible.
Signs Of Inflammatory Breast Cancer
Another type of breast cancer, known as inflammatory breast cancer , will only rarely cause lumps or symptoms. This type of breast cancer does not show up on a mammogram. Symptoms of inflammatory breast cancer may include:
- Red, swollen, itchy breast
- Tenderness of the breast when touched
- A pitted or ridged appearance of the surface of the breast
- Aching, burning, heaviness in one breast
- One breast that is significantly larger than the other breast
- A nipple that faces inward
- Swollen lymph nodes under the arm
- Swollen lymph nodes above the collarbone
- Other symptoms that do not go away after you take a course of antibiotics
It is important to remember that several other conditions besides cancer can cause these changes. Eczema can cause changes to the texture of the skin on your breasts, for example, and many illnesses can cause swollen lymph nodes. Breasts may change size during your menstrual cycle, inverted or flat nipples throughout life are common, and milk leaks are very normal during pregnancy or shortly after you have had a baby.
If you notice changes in the size of only one breast, skin changes not associated with eczema, changes in the size or shape of only one breast, or have nipple discharge when you are not pregnant or during postpartum, however, you should seek a medical opinion. Other signs to look for are nipples that invert or flatten suddenly or a feeling of warmth inside your breast.
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Stage 4 Breast Cancer
Stage 4 breast cancer can have a tumor of any size. Its cancer cells have spread to nearby and distant lymph nodes as well as distant organs.
The testing your doctor does will determine the stage of your breast cancer, which will affect your treatment.
Although they generally have less of it, men have breast tissue just like women do. Men can develop breast cancer too, but its much rarer.
According to the ACS , breast cancer is 70 times less common in Black men than in Black women. Its 100 times less common in white men than in white women.
That said, the breast cancer that men develop is just as serious as the breast cancer that women develop. It also has the same symptoms. If youre a man, follow the same monitoring instructions as women and report any changes to breast tissue or new lumps to your doctor.
N Categories For Breast Cancer
N followed by a number from 0 to 3 indicates whether the cancer has spread to lymph nodes near the breast and, if so, how many lymph nodes are involved.
Lymph node staging for breast cancer is based on how the nodes look under the microscope, and has changed as technology has gotten better. Newer methods have made it possible to find smaller and smaller groups of cancer cells, but experts haven’t been sure how much these tiny deposits of cancer cells influence outlook.
Its not yet clear how much cancer in the lymph node is needed to see a change in outlook or treatment. This is still being studied, but for now, a deposit of cancer cells must contain at least 200 cells or be at least 0.2 mm across for it to change the N stage. An area of cancer spread that is smaller than 0.2 mm doesn’t change the stage, but is recorded with abbreviations that indicate the type of special test used to find the spread.
If the area of cancer spread is at least 0.2 mm , but still not larger than 2 mm, it is called a micrometastasis . Micrometastases are counted only if there aren’t any larger areas of cancer spread. Areas of cancer spread larger than 2 mm are known to influence outlook and do change the N stage. These larger areas are sometimes called macrometastases, but are more often just called metastases.
NX: Nearby lymph nodes cannot be assessed .
N0: Cancer has not spread to nearby lymph nodes.
N1c: Both N1a and N1b apply.
N3: Any of the following:
N3a: either:
N3b: either:
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