What Is The Worst Type Of Breast Cancer To Have

Common Breast Cancer Types

After skin cancer, breast cancer is the most common type of cancer diagnosed in women. About 284,200 cases will be diagnosed in 2021, according to the American Cancer Society . Men also may develop breast cancer, though its much more rare.

Breast cancer is classified into different types based on how the cells look under a microscope. Most breast cancers are carcinomas, a type of cancer that begins in the linings of most organs.

The Types Of Cancer With The Best And Worst Survival Rates

Men with prostate cancer, 85.5 per cent survived for five years, followed 85.4 per cent of women with breast cancer

Cancer survival rates are improving in Grimsby and Cleethorpes but there are still big variations.

Men with prostate cancer have the best survival rate locally with 96.4 per cent of those diagnosed between 2012 and 2016 surviving a year, followed by women with breast cancer, with 95.7 per cent surviving a year.

In comparison, less than half of those diagnosed with oesophagus , stomach , and lung cancers survived a year.

The gap is even bigger when looking at five-year survival rates in the area.

For men with prostate cancer, 85.5 per cent survived for five years, followed 85.4 per cent of women with breast cancer.

This compares to 12.5 per cent of people with lung cancer and 16.2 per cent of people with stomach cancer.

However, the five-year survival rate for lung cancer has significantly improved from 9.6 per cent for those diagnosed between 2007 and 2011.

Overall, five-year survival rates in the area have improved for 11 out of 14 common cancers between 2007 to 2011 and 2012 to 2016.

Estimates are age-standardised to adjust for changes in the age profile of cancer patients over time and differences between geographical areas.

Sarah Caul, Head of Cancer Analysis, said: In general, we have seen an increase in peoples chances of survival across different types of cancer since our estimates for 2006 to 2010.

Genetic Breast Cancer Testing Recommendations

Some inherited genes can mutate and increase the risk of breast cancer. The most important of these genes are BRCA1 and BRCA2. Genetic testing can find mutations in these genes and may be recommended for people with:

• A known family history of a BRCA mutation
• A family history of breast cancer at a young age
• Ashkenazi Jewish decent
• Women diagnosed with breast cancer at a young age , regardless of family history

Not every woman needs to be tested. A doctor will be able to advise whether genetic testing would be appropriate.

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Breast Cancer Survival Rates According To The Stage Of The Cancer

Breast cancer stage of course refers to the spread and size of cancer at diagnosis. Stage zero means the breast cancer is still in situ or contained. Whereas, stage IV means that the cancer has metastasised to other body regions. The stage of cancer at diagnosis affects prognosis.

The statistics below are taken from the from the SEER database of the National Cancer Institute between the years 1975 to 2010.

The 5 year survival rate means that within 5 years around 93 people out of 100, diagnosed with Stage II breast cancer, will still be alive.

Breast Cancer Cell Lines

Part of the current knowledge on breast carcinomas is based on in vivo and in vitro studies performed with cell lines derived from breast cancers. These provide an unlimited source of homogenous self-replicating material, free of contaminating stromal cells, and often easily cultured in simple standard media. The first breast cancer cell line described, BT-20, was established in 1958. Since then, and despite sustained work in this area, the number of permanent lines obtained has been strikingly low . Indeed, attempts to culture breast cancer cell lines from primary tumors have been largely unsuccessful. This poor efficiency was often due to technical difficulties associated with the extraction of viable tumor cells from their surrounding stroma. Most of the available breast cancer cell lines issued from metastatic tumors, mainly from pleural effusions. Effusions provided generally large numbers of dissociated, viable tumor cells with little or no contamination by fibroblasts and other tumor stroma cells.Many of the currently used BCC lines were established in the late 1970s. A very few of them, namely MCF-7, T-47D, MDA-MB-231 and SK-BR-3, account for more than two-thirds of all abstracts reporting studies on mentioned breast cancer cell lines, as concluded from a Medline-based survey.

Metabolic markers

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Related Questions Answered On Yanswers

POLL In your opinion, What is the worst cancer you could have?

Q: a friend has cancer of the colen, he says its the worst of them

A: I have heard , from men , that prostate cancer is the worst. But really, what would be the best type of cancer? None im sure. But I have seen , personally, that lung cancer kicks butt! It effects the breathing. Its one thing to be really sick, then its another not be able to breathe.

what is the worst cancer in the usa?

Q: is pancreatic cancer the the most deadliest cancer in the usa?

A: No. In terms of new cases, lung cancer is thethird most common form of cancer, behindbreast and prostate cancers. But in termsof deaths, lung cancer kills the most peopleby far more than breast, colon, pancreasand prostate cancer combined. Andbecause Kentucky, Ohio and Indiana havesome of the nations highest smokingrates, lung cancer incidence and deathsin this region remain higher than nationalaverage.Lung cancer

Adenoid Cystic Carcinoma Of The Breast

Less than 1 in 100 breast cancers are adenoid cystic cancer. This type of cancer is also sometimes called a cribriform cancer. It is a cancer type that is more often diagnosed in the salivary glands, but some develop in the breast tissue.

It is generally seen in older people but has been seen in people as young as 25.

Adenoid cystic breast cancer tends to be slow growing. Doctors usually recommend surgery. Most women dont need to have the whole breast removed . Instead, your doctor will just remove the area of the cancer. This operation is called breast conserving surgery.

The cancer rarely spreads elsewhere in the body. So you don’t usually need to have your lymph nodes removed. The risk of this type of tumour coming back is low, so the outlook is good.

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What Is A 5

A relative survival rate compares women with the same type and stage of breast cancer to women in the overall population. For example, if the 5-year relative survival rate for a specific stage of breast cancer is 90%, it means that women who have that cancer are, on average, about 90% as likely as women who dont have that cancer to live for at least 5 years after being diagnosed.

What Is Stage Ii Breast Cancer

Stage II describes cancer that is in a limited region of the breast but has grown larger. It reflects how many lymph nodes may contain cancer cells. This stage is divided into two subcategories.

Stage IIA is based on one of the following:

• Either there is no tumor in the breast or there is a breast tumor up to 20 millimeters , plus cancer has spread to the lymph nodes under the arm.
• A tumor of 20 to 50 millimeters is present in the breast, but cancer has not spread to the lymph nodes.

Stage IIB is based on one of these criteria:

• A tumor of 20 to 50 millimeters is present in the breast, along with cancer that has spread to between one and three nearby lymph nodes.
• A tumor in the breast is larger than 50 millimeters, but cancer has not spread to any lymph nodes.

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The Precuneus And Its Neighbors

Although a relatively unstudied area of the brain, the precuneus role appears to be an important one. The precuneus and surrounding areas have the highest resting metabolic rates in the brain a sure sign that they have a lot of work to do.

It is thought to play a role in a number of integrated tasks, including visuospatial imagery and the retrieval of episodic memories.

Connections between the precuneus and the frontal, hippocampal and lateral parietal regions were found to be lacking in the anthracycline-based groups brains. This lack of linkage is thought to disrupt the efficiency of information processing and lessen dynamic responses in cognitive tasks.

As for the mechanisms at work in degenerating connectivity in these specific brain regions, that is up for debate. One theory involves cytokines. Anthracycline-based chemotherapy has been found to release more proinflammatory cytokines, causing increased neuroinflammation that may be to blame.

Another avenue of interest might be the effects of oxidative stress on the brain. Chemotherapy has been found to produce reactive oxygen species and, at the same time, reduce the patients ability to react and clear the destructive agents. This could lead to direct damage of the neurons.

The authors conclude:

Chemotherapy, its effectiveness and its consequences are rightfully under constant scrutiny. With time, no doubt, the chemobrain phenomenon will become well understood and preventable.

What Is Stage Iii Breast Cancer

In stage III breast cancer, the cancer has spread further into the breast or the tumor is a larger size than earlier stages. It is divided into three subcategories.

Stage IIIA is based on one of the following:

• With or without a tumor in the breast, cancer is found in four to nine nearby lymph nodes.
• A breast tumor is larger than 50 millimeters, and the cancer has spread to between one and three nearby lymph nodes.

In stage IIIB, a tumor has spread to the chest wall behind the breast. In addition, these factors contribute to assigning this stage:

• Cancer may also have spread to the skin, causing swelling or inflammation.
• It may have broken through the skin, causing an ulcerated area or wound.
• It may have spread to as many as nine underarm lymph nodes or to nodes near the breastbone.

In stage IIIC, there may be a tumor of any size in the breast, or no tumor present at all. But either way, the cancer has spread to one of the following places:

• ten or more underarm lymph nodes
• lymph nodes near the collarbone
• some underarm lymph nodes and lymph nodes near the breastbone
• the skin

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Infiltrating/invasive Lobular Breast Carcinoma

Infiltrating lobular carcinoma usually appears as a subtle thickening in the upper-outer breast quadrant.

As the name suggests, these tumours originate mostly in the breast lobules rather than the lining of the breast ducts.

Invasive lobular cancer is a less common type of breast cancer than invasive ductal cancer. This cancer accounts for about 10% of all invasive breast cancer cases.

Prognosis for infiltrating and invasive lobular breast carcinomas will naturally be influenced by tumor size, grade, stage and hormone receptor status..

However, lobular breast cancers, when positive for estrogen and progesterone receptors, tend to respond very well to hormone therapy.

The overall breast cancer survival rates for infiltrating lobular carcinoma, when matched by stage, are a little higher than for ductal carcinoma for the first 5 years.

Survival rates range from about 77% to 93%, but on average, the 5-year survival rate was estimated at about 90%.

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Outlook For People With Stage 3 Breast Cancer

Its natural to want to know your outlook, but statistics dont tell the whole story. Your breast cancer type, overall health, and many more factors beyond your control may affect treatment outcomes.

Establishing open communication with your treatment team can help you best assess where you are in your cancer journey.

Support groups can be a great source of comfort as you navigate your diagnosis through your treatment and beyond. Your doctors office or hospital can offer some suggestions and resources in your area.

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Rare Forms Of Invasive Ductal Carcinoma

While invasive ductal carcinoma is generally common, below are four types of invasive ductal carcinoma that are less common:

Medullary ductal carcinoma: This type of cancer is rare and accounts for 3 percent to 5 percent of breast cancers. It is called medullary because, under a microscope, it resembles part of the brain called the medulla. Medullary carcinoma may occur at any age, but it typically affects women in their late 40s and early 50s. Medullary carcinoma is more common in women who have a BRCA1 gene mutation. Medullary tumors are often triple-negative, which means they test negative for estrogen and progesterone receptors and for the HER2 protein. Medullary tumors are less likely to involve the lymph nodes, are more responsive to treatment, and may have a better prognosis than more common types of invasive ductal cancer.

Surgery is typically the first-line treatment for medullary ductal carcinoma. A lumpectomy or mastectomy may be performed, depending on the location of the tumor. Chemotherapy and radiation therapy may also be used.

Surgery is typically recommended to treat mucinous ductal carcinoma. A lumpectomy or mastectomy may be performed, depending on the size and location of the tumor. Adjuvant therapy, such as radiation therapy, hormonal therapy and chemotherapy, may also be required. Because most mucinous carcinomas test negative for receptors for the protein HER2, they arent typically treated with trastuzumab .

What Is The Grade Of My Tumor

Grading is not the same as staging. Both are indicators of a cancers severity and prognosis, but they use different criteria. Staging deals with the tumor size, location and the distribution of cancer cells in your body. But grading is based on how the cancer cells appear under a microscope.

The more abnormal-looking the cells are, the more likely they are to quickly grow and spread. Grades usually run from I to III. A higher grade is a more aggressive cancer. Its possible to have a Stage I tumor thats also a Grade III cancer.

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Top 10 Worst Types Of Cancer To Have

Cancer. Theres a reason people dread hearing the bad C-word from their doctor: its a deadly disease. In fact, cancer is the top cause of death right behind heart attacks and strokes.

If youve never known anyone who died of cancer, you can consider yourself lucky. Most people have family members, friends, or colleagues who developed cancer and died. Cancer is the leading cause of death in the world. There are many different treatments depending on which type of cancer it is, so its important to know the worst types of cancer to know how to treat it.

This list contains the top ten worst types of cancer to have:

If I Have Chemotherapy Will I Need To Take Other Medications Like Trastuzumab

If your breast cancer is HER2-positive, its recommended that you take trastuzumab for one year, Dr. Abraham says. This ensures that the HER2 growth receptor on any remaining cancer cells stays shut off. Trastuzumab is not chemotherapy. The hair you lost during chemotherapy will regrow and your energy level will improve while youre taking trastuzumab.

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Foods That May Lower Breast Cancer Risk

Keep in mind that many factors are associated with breast cancer development. While improving your diet can improve your overall health and reduce your cancer risk in general, its only one piece of the puzzle.

Even with a healthy diet, you still need regular breast cancer screenings like mammograms and manual checks. After all, early detection and diagnosis significantly increase survival rates. Talk to your healthcare provider for advice about breast cancer screenings.

All the same, research suggests that these foods may lower your risk of this disease.

What Is The Stage Of My Cancer

Cancer staging is a standardized way of classifying the severity of a patients cancer. There are various systems that use number or letter codes to designate the cancers status and how far it may have spread.

You may have heard of Stages 0 through IV, which reflect a tumors size and the extent of metastasis. A higher stage means a larger tumor and wider distribution of cancer cells.

Your doctor uses staging to plan your treatment, gauge your prognosis and communicate with other cancer specialists. What stage your cancer is in also will help determine whether youre eligible for clinical trials which offer newer treatment options.

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What Is The Worst Cancer To Have

What is the worst cancer to have

What is the worst type of cancer?

http://answers.yahoo.com/question/index?qid=20090527110853AAm7ZEv

Pancreatic cancer is the worst form of cancer. My mother died from Ovarian cancer. That is painful too. Cancer is my biggest fear! It is the one thing I hope I never develop. Someday, we will look back at cancer the way we do at TB deadly,

How bad can skin cancer get

http://www.answerbag.com/q_view/675466

I found a small uneven spot on my shin when I was 28 I knew it was cancer, I went and had a biopsy and sure enough it was the worst, malignant melanoma, I had surgery, where they were able to remove it all,

Are the side effects of chemotherapy worse than the cancer??

http://fryemedctr.staywellsolutionsonline.com/outcomeimprovement/cancer/general/FAQ.pg?PrinterFriendly=true

Chemotherapy has been used for many years, and only in the last 10 years or so have researchers really understood how the side effects occur. Nausea and vomiting, which to many are the worst of the side effects, can be controlled for most p